Clinical information including rubor, calor, and functio laesa
was not available for two children.
On clinical examination we suspected a local infection due to the presence of the Celsian clinical features for acute inflammation, represented by pain, swelling, local heat, erythema, and movement disorder with partial loss of function (functio laesa
The signs of the inflammatory response (rubor, tumor, calor, dolar, and functio laesa
) are induced by vascular changes & cellular changes.
Only edema (tumor) and, frequently, impairment of functions (functio laesa
) are noted.
Western medicine first recognized the four signs of inflammation 2000 years ago as tumor, rubor, calor and dolor, Latin for "swelling," "redness," "heat," and "pain." Galen, the Alexandrian physician redactor, a few hundred years later added functio laesa
, Latin for "loss of function," as the fifth aspect or consequence of inflammation.