We found statistically significant correlations between increased resistance to 5-fluorocytosine and higher activity of naphthyl phosphohydrolase and lipase; increased resistance to miconazole and higher activity of beta-glucosidase; increased resistance to fluconazole and higher activity of alpha-glucosidase, alpha-galactosidase, and fucosidase. Other correlations were statistically insignificant.
In the case of isolates from mobile phone surfaces, we generally showed statistically significant correlations between increased resistance to 5-fluorocytosine, miconazole, fluconazole, ketoconazole, itraconazole and higher enzymatic activity of alpha-galactosidase, alpha-glucosidase, alpha-mannosidase, beta-glucuronidase, beta-glucosidase, chymotrypsin, naphthyl phosphohydrolase, fucosidase, lipase, and esterase lipase.
Deficiency of fucosidase
results in acrosomal dysgenesis and impaired sperm maturation.
Enzymes that were semiquantifiable were phospholytic (alkaline phosphatase, acid phosphatase, and naphthol-AS-BI-phosphohydrolase), glyocolytic ([beta]-galactosidase, NAGase, fucosidase
) or proteolytic (leucine arylamidase).
Szajda et al., "Alpha fucosidase
and beta galactosidase in serum of a lyme disease patients as a possible marker of accelerated senescence--a preliminary study," Folia
(23) Other enzymes like mannosidase, fucosidase
, hexosaminidase and sialidase also is elevated that expose buried adhesion receptors on mucosal epithelium thus increasing the adhesion of Gram negative bacteria this foster increased adhesion and colonization by respiratory pathogens.
Keywords: FUCA1 evolutionary analysis bat molecular cloning glycosidase glycoside hydrolase fucosidase
Forty-five minute treatment of TIMP-1 with [alpha]1-2 fucosidase
, an enzyme that hydrolyzes the [alpha]1-2 linked fucose that UEA preferentially recognizes, decreased the fluorescence signals of TIMP-1 measured by the UEA LISA at various concentrations compared to those without the treatment (see online Supplemental Fig.