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A loop diuretic that acts by inhibiting reabsorption of sodium and chloride in the ascending loop of Henle. Produces profound diuresis with increased excretion of calcium, magnesium, bicarbonate, ammonium, and phosphate.
Farlex Partner Medical Dictionary © Farlex 2012
frusemideFurosemide, a drug that causes an increased output of urine (a diuretic) so as to relieve the body of unwanted retained water (oedema). Furosemide is a loop diuretic. It acts on the kidney tubules where it interferes with chloride and sodium reabsorption from the dilute filtered urine. This prevents reabsorption of water into the blood and the result is a large volume of dilute urine. The drug is on the WHO official list. Brand names are Froop, Frusol, Frusix and Lasix. The drug is one of the ingredients in a range of diuretic preparations such as Diumide-K Continus, Fru-Co, Frumil, Frusene, Lasikal, Lasilatone and Lasoride.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005