frozen section


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frozen section

 
a specimen of tissue that has been quick-frozen, cut by microtome, and stained immediately for rapid diagnosis of possible malignant lesions. A specimen processed in this manner is not satisfactory for detailed study of the cells, but it is valuable because it is quick and gives the surgeon immediate information regarding the malignancy of a piece of tissue.

fro·zen sec·tion

a thin slice of tissue cut from a frozen specimen, often used for rapid microscopic diagnosis.

frozen section

Cryostat section, 'frozen,' quick section Surgical pathology A rapid diagnostic procedure performed on tissue obtained intra-operatively, which is frozen in a synthetic material–eg, OCT–Miles Labs, sectioned with a cryostat, stained with H&E and viewed with a LM, allowing a rapid diagnosis of a pathologic tissue; a FS provides a surgeon with information necessary to guide therapy, and to determine the extent of further surgery at the time of surgical procedure
Frozen section–indications
1. Differentiate between benign and malignant
.
2. Determine type of malignancy–eg, lymphoma v. carcinoma
.
3. Evaluate tissue margins for involvement by malignancy, eg basal cell carcinomas
.
4. Determine adequacy of tissue for further studies after the Pt is closed
.
5. Determine type of tissue, eg differentiate lymphoid tissue from parathyroid gland
.

fro·zen sec·tion

(frō'zĕn sek'shŭn)
A thin slice of tissue cut from a frozen specimen, often used for rapid microscopic diagnosis.

frozen section

A method of obtaining a while-you-wait opinion on a BIOPSY specimen. The tissue block is frozen solid with dry ice so that thin slices can be cut, mounted on slides, stained and immediately examined under the microscope. Frozen sections are often called for in the course of an operation for suspected cancer. The result may radically alter the surgical procedure performed.
References in periodicals archive ?
Imprint cytology versus frozen section in intraoperative diagnosis of thyroid swellings.
This information is currently determined with intraoperative frozen sections, in which a small fraction of the surgical specimen is frozen, stained, and assessed microscopically to answer whether a completion lobectomy should be performed instead of a wedge resection.
Squash cytology in neurosurgical practice: A useful method in resource-limited setting with lack of frozen section facility.
The aim of the present study was to evaluate the margin status of resected specimens on frozen sections and the impact of R1 resection margin on survival.
All the designated margins were taken and labelled slides of each designated margin were prepared using the standard protocol of frozen section, followed by HandE staining.
Routine intraoperative frozen section examination must be applied in all patients with an increased risk of malignancy in a thyroid nodule (15,16,17).
In case there was positive report on frozen section by pathologist, further resection of the suspected tissue was carried out till a negative margin was achieved.
Fleuren, "The accuracy of frozen section diagnosis of ovarian tumors," Gynecologic Oncology, vol.
Frozen section is a technique which ensures clean surgical margins during excision.
Frozen section evaluation of stereotactic brain biopsies: diagnostic yield at the stereotactic target position in 188 cases.
headquarters in Los Angeles, usually offers its gluten-and wheat-free breads in the frozen section, but lately it's been trying something different.
"By performing frozen sections instead, crystals are well preserved and allow us to see their disposition."