Frontal lobe syndrome or dysexecutive syndrome, which occurs as a result of frontal lobe injury, presents as a specific entity including the symptoms such as disorders in executive function, abstract thinking, speech production and personality, and emotional changes (e.g., reduced self-control and self-direction, lack of criticism, emotional instability, apathy, irritability, excitability, disinhibition in expressing emotions, socially improper behavior and ignoring of social rules, and changes in sexual behavior)(1).
The 4-degree scale was used for clinical assessment of organic personality changes, or frontal lobe syndrome: 0 denoting no symptoms of frontal lobe syndrome, 1 for mild, 2 for moderate, and 3 for severe frontal lobe syndrome.
Frontal lobe syndrome is defined as a set of changes in the cognitive, behavioral, or emotional domains, often leading to disturbed affect, alteration of attention, aphasia, perseveration, disinhibition, and personality changes.
Medications for frontal lobe syndrome include typical and atypical antipsychotics, dopamine agonists, and mood stabilizers
Given his clinical picture, recent history of neurological disorder and findings on neuroimaging studies, we made a provisional diagnosis of KBS and frontal lobe syndrome. He was started on haloperidol 0.5-1 mg/day for behavioral control.
We think that diffuse infarcts over the right hemisphere, including the frontal lobe, may account for the presence of latter symptoms as it is mentioned above that frontal lobe syndrome may include this kind of symptoms.