Two patients are frontal lobe epilepsy
with hippocampus origin (frontal/H, short to be FLE), four patients are temporal epilepsy with hippocampus origin (temporal/H, short to be TLE), and two patients are temporal, occipital epilepsy with hippocampus origin (temporooccipital/H).
KEY WORDS: Prefrontal cortical functioning; Cognition; Empathy; Executive functions; Frontal lobe epilepsy
Pediatric frontal lobe epilepsy
: White matter abnormalities and cognitive impairment.
Goodyear et al., "Frontal lobe epilepsy
alters functional connections within the brain's motor network: a resting-state fMRI study," Brain Connection, vol.
Surgery for central area and frontal lobe epilepsy
is challenging and is usually less successful than that for temporal lobe epilepsy.
(2002) examined the components of frontal lobe syndrome (impairments of planning abilities; working memory; impulse control; attention and certain aspects of motor coordination) in children with frontal lobe Epilepsy
(FLE) and found deficits in planning, without any gender difference.
* Frontal lobe epilepsy
. Sudden onset and termination of a cluster of very short seizures are the hallmarks of this type of epilepsy.
(9) FDG-PET may not be as valuable in the evaluation of patients with extra-temporal seizures, such as frontal lobe epilepsy
, because of limited sensitivity.
-- Patients with frontal lobe epilepsy
experience a very high incidence of psychiatric symptoms that can contribute to misdiagnosis and can unnecessarily delay treatment, Dr.
"They may feel that the only substances they can use to stay alert are caffeine and tobacco." Additionally, he said, patients with frontal lobe epilepsy
may have a disruption in executive functioning, including judgment.
Even with medication 25-35% of patients with epilepsy have break-through seizures; 75% have seizures during wake and sleep; and 20% of patients with epilepsy have seizures solely while asleep, many of them diagnosed with frontal lobe epilepsy
Investigators found two mutations that alter acetylcholine receptor genes; one mutation on chromosome 20 is believed responsible for autosomal dominant nocturnal seizures, and another mutation on chromosome 1 is implicated in seizures with frontal lobe epilepsy