dermorphin

(redirected from frog juice)

dermorphin

A hepta-peptide first isolated from the skin of South American frogs of the genus Phyllomedusa (e.g., P sauvagei), which is a highly potent opioid agonist with selectivity for mu opioid receptors. It is 30–40 times more potent than morphine but less likely to produce drug tolerance and addiction. It has been used illegally in horse racing as it deadens pain, allowing horses to run even if injured.
References in periodicals archive ?
Dermorphin, commonly known as frog juice because it occurs naturally in the skin of a South American frog, is a powerful painkiller, said to be 40 times more powerful than morphine.
* South Korean Park Ji-Sung The lobby group, Frogs Friends, said that consumption of frog juice surged after the United star revealed in his 2006 autobiography that he had drunk the liquid as a tonic.
London, Mar 23 (ANI): Ace midfielder Park Ji Sung, who played an crucial role in Manchester United's victory on Sunday, drank stinking boiled frog juice to become a man.
FRESHLY squeezed frog juice is putting a spring in the step of impotent Peruvian men.
Scientists and doctors around the world are learning to use "frog juice" to help cure human diseases.
"We've been aware of ITTP for a couple of years at least while frog juice we've known about for probably six months or so," says Morris.
The emergence of frog juice across the Atlantic is merely the latest in a long line of bizarre-sounding substances to have been the subject of rumour and innuendo following cone snail venom and cobra venom, both powerful painkillers that were said to have made their way on to racetrack backstretches.
"The key thing about frog juice is that it is a natural analogue of morphine and it is quite potent, so we are concerned about it for exactly the same reasons we are concerned about morphine," says Morris.
"But even if the frog juice simply returns a horse to normality so it isn't feeling any pain, it is still affecting the system.
"DON'T lick the back of a frog - you'll get a buzz all weekend and your horse will test positive!" Such is the response of one US racetrack veteran when asked if he knows anything about dermorphin - frog juice, in common parlance - the illegal substance at the centre of a number of positive tests in the States in recent weeks since a test was developed to detect the drug.
Three quarter-horse trainers based at Delta Downs have also been suspended for frog juice positives; more are expected to follow with transgressions reported in Oklahoma, New Mexico and possibly Texas.