acanthosis

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acanthosis

 [ak″an-tho´sis]
diffuse hypertrophy or thickening of the prickle cell layer of the skin. adj., adj acanthot´ic.
acanthosis ni´gricans diffuse acanthosis with gray, brown, or black pigmentation, chiefly in the axillae and other body folds, occurring in an adult form, often associated with an internal carcinoma (called malignant acanthosis nigricans) and in a benign, nevoid form, more or less generalized. A benign form associated with obesity, which is sometimes due to endocrine disturbance, is called pseudo-acanthosis nigricans. (See Atlas 2, Part E).
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ac·an·tho·sis

(ak-an-thō'sis),
An increase in the thickness of the stratum spinosum of the epidermis.
[G. fr. acantho-, thorn + G. -osis, condition]
Farlex Partner Medical Dictionary © Farlex 2012

acanthosis

Hyperplasia of the squamous epithelium of mucocutaneous surfaces.
Diseases with
Psoriasis, granulomatous reactions, lymphocytic infiltrates.

Mechanism
Defective epidermal cell kinetics.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

ac·an·tho·sis

(ak-an-thō'sis)
An increase in the thickness of the stratum spinosum of the epidermis.
[G. fr. acantho-, thorn + G. -osis, condition]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

acanthosis

A disease process in the skin featuring overgrowth and thickening of the prickle-cell layer of the EPIDERMIS. This layer lies above its parent layer, the BASAL cell layer, and local overgrowth results in raised, roughened areas such as warts or the lesions of PSORIASIS or ECZEMA.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

ac·an·tho·sis

(ak-an-thō'sis)
Increased thickness of epidermal stratum spinosum.
[G. fr. acantho-, thorn + G. -osis, condition]
Medical Dictionary for the Dental Professions © Farlex 2012