fresh frozen plasma

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Related to fresh frozen plasma: Platelet transfusion


1. the fluid portion of the lymph.
2. the fluid portion of the blood, in which the formed elements (blood cells) are suspended. Plasma is to be distinguished from serum, which is plasma from which the fibrinogen has been separated in the process of clotting. Called also blood plasma. adj., adj plasmat´ic, plas´mic.

Of the total volume of blood, 55 per cent is made up of plasma. It is a clear, straw-colored liquid, 92 per cent water, in which are contained plasma proteins, inorganic salts, nutrients, gases, waste materials from the cells, and various hormones, secretions, and enzymes. These substances are transported to or from the tissues of the body by the plasma.

Plasma obtained from blood donors is given to persons suffering from loss of blood or from shock to help maintain adequate blood pressure. Since plasma can be dried and stored in bottles, it can be transported almost anywhere, ready for immediate use after addition of the appropriate fluid. Plasma can be given to anyone, regardless of blood type. (See also transfusion.)

Plasma volume is sometimes measured in order to calculate the total blood volume. The most common method for determining plasma volume is by injection of a dye (T-1824, called Evans blue) into the circulating blood and, after the dye has been dispersed throughout the body, using the dilution of the dye to calculate the total blood volume.
antihemophilic human plasma normal human plasma that has been processed promptly to preserve the antihemophilic properties of the original blood; used for temporary correction of bleeding tendency in hemophilia.
blood plasma plasma (def. 2).
citrated plasma blood plasma treated with sodium citrate, which prevents clotting.
plasma exchange the removal of plasma from withdrawn blood (plasmapheresis) and retransfusion of the formed elements and type-specific fresh frozen plasma into the donor; done for removal of circulating antibodies or abnormal plasma components.
fresh frozen plasma plasma separated from whole blood and frozen within 8 hours; it contains all the coagulation factors.
plasma thromboplastin antecedent deficiency hemophilia C.

fresh fro·zen plas·ma (FFP),

separated plasma, frozen within 6 hours of collection, used in hypovolemia and coagulation factor deficiency.

fresh frozen plasma

Etymology: ME, fresen, to be cold; Gk, plassein, to mold
plasma separated from whole blood and frozen within 8 hours of collection. FFP has a shelf life of 12 months when stored at 18C or below. It contains normal levels of all the coagulation proteins, including the labile factors V and VIII. See also plasma.

fresh frozen plasma

Therapeutics A blood component, separated from whole blood which provides 80-120 mg of fibrinogen and ≥ 80 units each of factors VIII and XIII Indications PT > 16 secs, acute liver decompensation, massive hemorrhage, transfusions where > 10 units of packed RBCs cause coagulation factor depletion; FFP is administered pre-operatively in Pts with coagulopathies–eg hemophilia B, in therapeutic apheresis, DIC, ITP, TTP, HDN

fresh fro·zen plas·ma

(FFP) (fresh frōzĕn plazmă)
Separated plasma, frozen within 6 hours of collection; used in hypovolemia and coagulation factor deficiency.

fresh fro·zen plas·ma

(fresh frōzĕn plazmă)
Separated plasma, frozen within 6 hours of collection, used in hypovolemia and coagulation factor deficiency.
References in periodicals archive ?
In fact, 17 of our 23 preventable deaths didn't get any fresh frozen plasma at all," she said.
In addition to the implicated unit of platelets, fresh frozen plasma was also derived from the original donation but was not transfused.
The collective nephrology nurses from the acute hemodialysis unit at a major metropolitan hospital anecdotally noted that clients who did not receive diphenhydramine prior to initiation of fresh frozen plasma (FFP) plasmapheresis seemed to have a higher incidence of transfusion-related reactions.
Fresh frozen plasma (FFP) is among the options for treatment in KMS as well as steroid therapy.
One protocol suggests transfusion of 2 units of fresh frozen plasma (FFP) for every 4 units of packed red blood cells (PRBC), a pooled unit of random platelets after every 8th PRBC and a 10-pack cryoprecipitate by the 16th PRBC.
The Central Blood Bank processes blood into various components, including packed red blood cells that last up to 45 days, platelets, which last for five days and are mainly used for leukaemia and hematological malignancy patients, fresh frozen plasma and cryoprecipitate.
The patient reported having been treated for episodes of excessive bleeding with fresh frozen plasma (FFP) (3) and factor VIII during past hospitalizations.
Improvement in fresh frozen plasma transfusion practice: results of an outcome audits.
Chilaley ordered vitamin K and additional platelets, and fresh frozen plasma in an effort to prevent further bleeding.
If his prothrombin time and partial thromboplastin time are abnormal, fresh frozen plasma may help correct a clotting factor deficiency.