free-radical theory of aging


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free-radical theory of aging

a concept of aging based on the premise that the main causative factor is an imbalance between the production and elimination in the body tissues of free chemical radicals from oxygen metabolism.
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Free-radical theory of aging

free-rad·i·cal the·o·ry of ag·ing

(frēradi-kăl thēŏr-ē ājing)
The proposition that organisms age because they accumulate free radicals, which are the products of oxidation reactions, over the course of time.
References in periodicals archive ?
Harman, "Nutritional Implications of the Free-Radical Theory of Aging," J.
Among the numerous hypotheses developed to understand the aging process, the free-radical theory of aging has become especially prominent (Harman, 1956).
Translated into daily life by Harman's free-radical theory of aging, a rising concentration of free radicals in the human body means that cells are damaged and die, a slew of diseases tends to set in, and the body ages and ultimately dies.
The free-radical theory of aging is based on the hypothesis that the endogenous build-up of free-radical species results in oxidative molecular damage.