framework region

in immunology, a conserved sequence of amino acids on either side of the hypervariable regions in the variable domains of an immunoglobulin chain.

Farlex Partner Medical Dictionary © Farlex 2012

frame·work re·gion

(frām'wŏrk rē'jŭn)

immunology A conserved sequence of amino acids on either side of the hypervariable regions in the variable domains of an immunoglobulin chain.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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alemtuzumab
Humanization

References in periodicals archive ?

Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

AstraZeneca obtains United States patent

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