framework region

framework region

in immunology, a conserved sequence of amino acids on either side of the hypervariable regions in the variable domains of an immunoglobulin chain.
Farlex Partner Medical Dictionary © Farlex 2012

frame·work re·gion

(frām'wŏrk rē'jŭn)
immunology A conserved sequence of amino acids on either side of the hypervariable regions in the variable domains of an immunoglobulin chain.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Mentioned in ?
References in periodicals archive ?
Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided.

Full browser ?