"Our data suggest that low micronutrient status has potential as an easily modifiable marker and intervention target for frailty
and supports further investigation into micronutrient supplementation and fortification to prevent frailty
and disability among older adults," the authors write.
In this new research lower levels of lutein, zeaxanthin, and vitamin D were consistently associated with not only frailty
but also earlier stages of 'pre-frailty' (a subclinical precursor of frailty
Furthermore, the accumulation of micronutrient insufficiencies -- having low levels of more than one micronutrient -- was progressively associated with severity stages of frailty
The findings "suggest that the risk of developing frailty
in older people is high.
Combining risk assessment tools such as the ASA-PS and frailty
assessments to improve postoperative risk prediction could increase the probability of correct identification of patients who are likely to suffer adverse intraoperative and postoperative adverse events, and has been suggested by some authors.
Although a higher number of chronic diseases is related to frailty
(2), our findings corroborated a previous study (24) that also observed high rates of those comorbidities in similar groups, although no difference was detected between them.
The company is now recruiting for an expanded Phase 2b aging frailty
However, we failed to calculate frailty
in 1.0% (n=8) and 6.0% (n=57) of the elderly for FRAIL and FFI, respectively, because of missing data.
is understood as a decreased physiologic reserve and an increased risk for adverse health outcomes.
Recognizing the challenges and opportunities to improve care for the frail, Primary Health Care and the Department of Family Practice, Nova Scotia Health Authority (NSHA) in collaboration with the Department of Medicine, and a broad group of community stakeholders began the development of what is now known as the NSHA Frailty
However, over the last two decades, the frailty
syndrome has been discussed mainly around two conceptual models and their respective instruments.
has been described the effects of natural ageing combined with the outcomes of multiple long-term conditions, a loss of fitness and reserves.