schistocyte

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Related to fragmented red cell: red cell fragmentation syndrome

schistocyte

 [shis´-, skis´to-sīt]
a fragment of an erythrocyte, commonly observed in the blood in hemolytic anemia; called also helmet cell and schizocyte.

schis·to·cyte

(skis'tō-sīt),
A variety of poikilocyte that owes its abnormal shape to fragmentation occurring as the cell flows through damaged small vessels.
Synonym(s): schizocyte
[schisto- + G. kytos, cell]

schistocyte

(shĭs′tə-sīt′)
n.
A red blood cell having an abnormal shape as a result of fragmentation that occurs as the cell flows through damaged small vessels.

schistocyte

A fragmented red cell which arises from either an intrinsic increase in cell fragility or due to intravascular rugosities that traumatise cells; schistocytes are a nonspecific finding seen in hemolysis, trauma, prosthetic heart valves, megaloblastic and microangiopathic anaemioccidianhemolytic uremic syndrome, TTP.

ker·a·to·cyte

(ker'ă-tō-sīt)
1. The fibroblastic stromal cell of the cornea.
2. A variety of poikilocyte that owes its abnormal shape to fragmentation occurring as the cell flows through damaged small vessels.
Synonym(s): schistocyte.

schistocyte

(skis'to-sit) [? + kytos, cell]
Enlarge picture
SCHISTOCYTE: In peripheral blood (×600)
A fragmented red blood cell that appears in the blood in a variety of bizarre shapes, from small triangular forms to round cells with irregular surfaces. Schistocytes are found in patients with hemolytic anemias, severe burns, and several other conditions. Synonym: schizocyte See: illustration
illustration
References in periodicals archive ?
Fragmented red cells or schistocytes (Figure 3--Slide E) often results from mechanical break-up/resealing of red cells in the periphery by microthrombi [35].
Red cell shapes Differential diagnosis Irreversibly sickled red Sickle cell syndromes(SS, SC, cells (drepanocytes) Spthalassemia) Target cells (codocytes, Sickle cell disease, haemoglobin mexican hat cells) C trait, haemoglobin CC disease, thalassemias, iron deficiency, Liver disease (cholestasis), asplenia, Fragmented red cells Thrombotic micro-angiopathic (schistocytes, helmet haemolytic anaemias such as cells, keratocytes) Disseminated intravascular coagulopathy (DIC), thrombotic thrombocytopenic purpura, haemolytic uraemic syndrome.
The blood film showed schistocytes and fragmented red cells and a diagnosis of TTP was first considered.
Her blood film showed fragmented red cells, which suggested the diagnosis of microangiopathic haemolytic anaemia.
Fragmented red cells were present on blood film on day 3.