foscarnet


Also found in: Dictionary, Wikipedia.
Related to foscarnet: foscarnet sodium, Foscavir

foscarnet

 [fos-kahr´net]
an agent that inhibits replication of viruses, used as the sodium salt in treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients.

foscarnet

/fos·car·net/ (fos-kahr´net) a virostatic agent used as the sodium salt in the treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients.

foscarnet

AIDS An antiviral for treating CMV colitis, hepatitis, pneumonia, retinitis; acyclovir resistant HSV, nonresponders to gancyclovir; foscarnet inhibits other herpes viruses and HIV; being studied for treatment of KS Adverse effects Renal damage, meatus rash, which may disappear even if foscarnet is discontinued. See AIDS. Cf ddC, ddI, Zidovudine.

foscarnet

A DNA POLYMERASE INHIBITOR drug used to treat severe herpes infections in immunocompromised people and cytomegalovirus internal eye infections in people with AIDS. A brand name is Foscavir.

foscarnet

a pyrophosphate analog used as an antiviral agent against herpesviruses.
References in periodicals archive ?
Severe encephalomyelitis in an immunocompetent adult with chromosomally integrated human herpesvirus 6 and clinical response to treatment with foscarnet plus ganciclovir.
Identification of crystals in kidneys of AIDS patients treated with foscarnet.
Se localizo una mutacion UL97, del CMV, especifica de resistencia a ganciclovir, en la muestra de tejido gastrico, por lo que se decide sustituir el gancicovir por a foscarnet.
Background: Foscarnet has been used for the treatment of cytomegalo virus (CMV) disease in HIV/AIDS and in peripheral stem cell transplant (PBSCT) patients with CMV disease.
Consider foscarnet therapy in patients with laboratory-documented resistant HSV.
Currently, 3 drugs have been approved for the treatment of this condition: ganciclovir, foscarnet, and cidofovir.
The antiviral drugs foscarnet and ganciclovir have been approved for treating people with AIDS-associated CMV retinitis.
The HIV-related medicines included AZT (Zidovudine), Zovirax (Acyclovir), Ganciclovir (DHPG), Amphotericin B, Dextran Sulfate, IVIG (Intravenous Gamma Globulin), Nebupent (Aerosol Pentamidine), Pentam (Pentamidine, IM, IV), Bactrim, Septra, Sulfadiazine, Pyrimethanine, Nystatin, Ampicillin, Amoxicillin, Isoniazid (INH), Fluconazole (Diflucan), Foscarnet, Ketoconazole (Nizoril), Rifampin (Rifadin), and Ciprofloxacin (Cipro).
For example, HIV-infected patients now receive bactrim or pentamidine for the treatment and prevention of Pneumocystis carinii pneumonia and ganciclovir and foscarnet to treat cytomegalovirus and herpes infections.
Two federally approved drugs, ganciclovir and foscarnet, fight CMV infection in people with AIDS.
Nonantiretrovirals requiring dose adjustment with declining kidney function * * Acyclovir * Adefovir * Amphotericin B * Cidofovir * Ciprofloxacin * Clarithromycin * Ethambutol * Famciclovir * Fluconazole * Flucytosine * Foscarnet * Ganciclovir * Isoniazid * Levofloxacin * Pentamidine * Pyrazinamide * Peginterferon alfa-2a * Peginterferon alfa-2b * Ribavirin * Rifabutin * Rifampin * Sulfadiazine * Trimethoprim/sulfamethoxazole * Valacyclovir * Valganciclovir * Source: HIVMA/IDSA CKD guidelines.