foscarnet


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Related to foscarnet: foscarnet sodium, Foscavir

foscarnet

 [fos-kahr´net]
an agent that inhibits replication of viruses, used as the sodium salt in treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients.

foscarnet

/fos·car·net/ (fos-kahr´net) a virostatic agent used as the sodium salt in the treatment of cytomegalovirus retinitis and herpes simplex in immunocompromised patients.

foscarnet

AIDS An antiviral for treating CMV colitis, hepatitis, pneumonia, retinitis; acyclovir resistant HSV, nonresponders to gancyclovir; foscarnet inhibits other herpes viruses and HIV; being studied for treatment of KS Adverse effects Renal damage, meatus rash, which may disappear even if foscarnet is discontinued. See AIDS. Cf ddC, ddI, Zidovudine.

foscarnet

A DNA POLYMERASE INHIBITOR drug used to treat severe herpes infections in immunocompromised people and cytomegalovirus internal eye infections in people with AIDS. A brand name is Foscavir.

foscarnet

a pyrophosphate analog used as an antiviral agent against herpesviruses.
References in periodicals archive ?
Foscarnet 24mg/ml intravenous infusion foscarnet 24mg/ml intravenous infusion presented in 250ml bottles.
Intravitreal pharmacokinetics and retinal concentrations of ganciclovir and foscarnet after intravitreal administration in rabbits.
In addition, there are also studies recommending oral valacyclovir and famciclovir, or intravenous foscarnet and gancyclovir as alternatives.
Unlike ganciclovir and valganciclovir, foscarnet is a phosphoric acid derivative that acts as a virostatic by inhibiting viral DNA polymerase and reverse transcriptase (SkidmoreRoth, 2016; Smith, 2016; Vallerand et al.
We describe here a difficult-to-treat case of CMV infection in a lung transplant recipient who did not show a sustained response after introduction of foscarnet, prompting switch to combined treatment based on cidofovir with CMVIG.
La deplecion de electrolitos debido a disfuncion tubular se ha asociado con multiples de medicamentos usados para el tratamiento de VIH e infecciones relacionadas, incluyendo el tenofovir, anfotericina, foscarnet y pentamidina.
Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis.
Objective: To compare the clinical effects of foscarnet sodium injection and interferon on human immunodeficiency virus (HIV)-infected patients complicated with herpes zoster.
Penciclovir cream, methylprednisolone (40 mg intravenous daily for two days, followed by a gradual taper of oral glucocorticoids), acyclovir (2105 mg intravenous for one day), foscarnet sodium (3 g daily for 11 days), and methycobal injection (1 mg daily for one week) were all administrated.
Nonantiretroviral drugs that can cause acute or chronic kidney injury Antibiotics Aminoglycoside antibiotics (streptomycin, gentamycin, amikacin) Beta-lactam antibiotics Fluoroquinolone antibiotics Sulfonamide antibiotics TMP-SMX (trimethoprim-sulfamethoxazole, cotrimoxazole, Bactrim, Septra) Dapsone (prevention of Pneumocystis pneumonia, treatment of acne, malaria, leprosy) Antivirals Acyclovir (herpes virus infections) Cidofovir (cytomegalovirus) Ganciclovir (cytomegalovirus) Foscarnet (cytomegalovirus, herpes simplex virus) Anti-TB drugs Rifampin Isoniazid Antifungals Amphotericin B (cryptococcal meningitis, thrush) Pentamidine (prevention of Pneumocystis pneumonia) Other agents Nonsteroidal antiinflammatories Phosphate-containing enemas Figure 1.
Misdiagnosis is detrimental because antiviral treatment for HHV-6 involves drugs, including ganciclovir, foscarnet, and cidofovir, which are costly and carry substantial side effects.
Sin embargo, no se ha encontrado relacion con el empleo de los inhibidores de la transcriptasa reversa, aunque otras drogas tendrian un rol importante en los cuadros de toxicidad en esta poblacion, como son la doxorrubicina, interferon alfa, foscarnet, cotrimoxazol, pentamidina y ganciclovir.