Also found in: Dictionary, Acronyms, Wikipedia.


A gene on chromosome 14q24.3 that encodes a leucine zipper DNA-binding FOS-type nuclear phosphoprotein, which dimerises with proteins of the JUN family to form the transcription factor complex AP1. FOS proteins regulate cell proliferation, differentiation and transformation, and may be associated with apoptosis.


A family of cancer-causing genes, first identified in viruses, that function within cells as transcription factors. Members of this family can transform normal cells (e.g., fibroblasts) into cancer cells (e.g., osteosarcomas, chondrosarcomas). See: oncogene; transformation


The name is derived from “FBJ osteosarcoma virus, ” in which these oncogenes were first identified.

References in periodicals archive ?
We were humbled by the great --success in the Florida markets, and we're now excited to bring FOS Greek Mastiha to the rest of the country," said Co-Founder Pierre Economacos of Ambrosia Group LLC.
For instance, we use failure mechanism III to illustrate the computational process of the upper bound solution of FOS.
If approved by the US FDA, Relypsa intends to commercialise Patiromer FOS with its own dedicated US based commercial team and specialty sales force of approximately 120 sales representatives.
However, many are now experiencing further delays in getting their money back with an increasing number of cases being referred to the FOS.
A spokeswoman for the FOS said there had been a "drag effect" on PPI complaints while the banking industry fought a legal battle on the issue.
A typical FOS class could include newly hired FS specialists and generalists who will be supervisors when they begin their overseas assignments.
The FOS upheld a complaint made and recommended the payment of damages in excess of pounds 90,000 to Brabners Chaffe Street's client by a Financial Services Authority (FSA) regulated finance company.
RPC says that the FSA recently contacted a sample of financial services firms to analyse how much redress they have been paying through FOS and court awards during the last year.
For the AECS-assisted technique, the operator passed the FOS via the LMA through the vocal cords and into the trachea.
Greek design firm F+M FOS delights in an artisanal approach
In a report to be handed to MEPs he concluded that FOS left complainants with an "entirely justifiable sense of disillusionment, frustration and injustice".