Discovery of chemical substances capable of acting as biochemical signals, and as mycorrhizal colonization biostimulant, such as the isoflavone formononetin
(NAIR et al.
Hypolipidemic principles of Cicer Arietinum: Biochanin-A and formononetin
That species is considered as an important source of bioactive compounds, mainly the isoflavones: daidzein, formononetin
and biochanin A (LOPEZ et al.
As a major isoflavone compound from Radix Astragali, formononetin
bearing the structure shown in Figure 1(a) exhibits a wide range of pharmacological properties such as anticancer [12,13], anti-inflammatory , antioxidant , antiviral , neuroprotective activities [17, 18], and wound healing .
It turned out that the clover was rich in a couple of natural estrogens: genistein and formononetin
Present study was aimed at determining the growth promoting and immune modulating effects of formononetin
Other studies have confirmed these results; before surgery, 20 men consumed 160 mg/day of red clover-derived dietary isoflavones, containing a mixture of genistein, daidzein, formononetin
, and biochanin A.
Significant or borderline associations between dietary phytoestrogens and bone density measured as BUA were found with the non soya isoflavones formononetin
in women (P 0.
2010): Simultaneous determination of formononetin
, biochanin A, daidzen and genistein in Trifolium pratense (Red Clover) by HPLC.
Following objections submitted by 10 European groups and by Israel-based Solbar, the EPO restricted claims, wherein the isoflavone phytoestrogen extract comprises genistein and daidzein (aglycones) from soybeans, and biochanin A or formononetin
in red clover, "in a ratio of about 1:2 to 2:1.
Following objections submitted by 10 European groups from Germany, France, Spain, Italy and the UK, and by Solbar (Israel), the EPO finally restricted claims wherein the isoflavone phytoestrogen extract comprises genistein and daidzein (aglycones) from soybeans and biochanin A or formononetin
in red clover "in a ratio of about 1:2 to 2:1.
Ademas, se realizo la extraccion de la corteza y descripcion estructural de un nuevo isoflavanoide 7,4'-dihydroxy-3'-methoxyisoflavan, de un extracto diclorometano y otros isoflavonoi des como isovertsol, formononetin
, afrormosin y una pterocarpan, medicarpin [Herath et al.