They are also a highly useful class of intermediates in the synthesis of pharmaceutically important compounds such as fluoroquinolines , cancer chemotherapeutic agents , oxazilidones , Vilsmeier-Haake formylation reaction , nitriles , hydrosilylation of carbonyl compounds , 1-arylimi-dazole-5-carboxylates , 1-formyl-1,2-dihydroquinolines , nitrogen bridged heterocycles , fungicides [8, 11], isocyanates , formamidines  and allylation reaction .
Cai, An Efficient and Convenient Synthesis of Formamidines, Tetrahedron Lett.
The four classes of chemical acaricides which are the mainstay of tick control programme in India are organophosphates, pyrethroids, formamidines and macrocyclic lactones.
The development of resistance against OP and SP acaricides has driven the farmers to rely on formamidines (amitraz) and macrocyclic lactones (ivermectin).
Influence of formamidines
on reproduction in twospotted spider mite (Acari: Tetranychidae).
Biochemical and molecular biological studies on the action of formamidines
in synergizing insecticidal action of pyrethroids and neonicotinoids in Aedes aegypti mosquitoes.
In the last several years, in the fight against parasites there have been used especially organophosphorus substances (Coumaphos), piretroides (Fluvilante) and formamidines
Chemicals that have historically been used to control ticks include organophosphates, carbamates, pyrethrins, synthetic pyrethroids, formamidines
, fipronil, and selamectin.