folinate


Also found in: Dictionary.

fo·li·nate

(fō'li-nāt),
A salt or ester of folinic acid.
Farlex Partner Medical Dictionary © Farlex 2012

fo·li·nate

(fō'li-nāt)
A salt or ester of folinic acid.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
CODOX-Mincluding cyclophosphamide, doxorubicin, vincristine, methotrexate, calcium folinate, granulocyte colony-stimulating factor, Ara-C and rituximab was prescribed, but uremia developed and HD was performed.
It is also known as folinic acid and is generally used as calcium or sodium folinate. Leucovorin does not cure cancer directly and is used as an adjunct to complement chemotherapy regimen.
(3) Bone myelosuppression, pancytopenia, agranulocytosis, inflammation and necrotic changes in mucous tissues, liver cell necrosis and hepatic cirrhosis, pulmonary fibrosis, disorders of kidney function, vasculitis and skin lesions are some side effects that may occur during the use of MTX.[1] When MTX is used in high doses, calcium folinate is the recommended rescue therapy.
However, at this state, doctors find that only the "high-dose methotrexate (HDMTX) + calcium folinate (CF) rescue" is not an ideal chemotherapy scheme for [P.sub.1].
Leucovirin (calcium folinate) in "antifreeze" poisoning.
Teva therefore agreed to dispose of the carboplatin and cisplatin businesses in the Czech Republic, Hungary and Slovenia, the fluorouracil business in the Czech Republic, the methotrexate businesses in the Czech Republic and Hungary, the paclitaxel businesses in the Czech Republic and Poland, the calcium folinate business in Poland, the tamoxifen business in Slovakia and Barr's calcium folinate business in the Czech Republic.
The FOLFIRI-3 regimen was administered every 14 days: on day 1 irinotecan, 100 mg/[m.sup.2], as a 1-hour infusion running concurrently with calcium folinate 400 mg/[m.sup.2], as a 2-hour infusion, followed by 5-FU, 2400 mg/[m.sup.2], as a 46-hour infusion.
The MTX was discontinued, calcium folinate was commenced and the dose of corticosteroids was increased.
After the transplant (allogenic in 9 cases and autogenic in 11 cases), patients received immunosuppressive drugs such as glucocorticosteroids (prednisone, 10-20 mg/day), cyclosporin, methotrexate, and calcium folinate. They also received granulocyte growth factors, antibiotics, antiviral and antifungal drugs, low-molecular weight heparinate (1000-10 000 units/day), and several comfort medications.
Multiagent chemotherapy was conducted as follows: 75 mg/[m.sup.2] docetaxel (EBEWE Pharma GmbH, Austria) on day 1 + 500 mg/[m.sup.2] 5-phthoruracil (Nantong Jinghua Pharmaceutical Co., China) on days 2-5 + 50 mg/[m.sup.2] calcium folinate (Hospira, USA) on days 2-5.