focal necrosis


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fo·cal ne·cro·sis

occurrence of numerous, relatively small or tiny, fairly well-circumscribed, usually spheroidal portions of tissue that manifest coagulative, caseous, or gummatous necrosis and are characteristically associated with agents that are hematogenously disseminated; frequently observed only in histologic sections, but the foci may be as large as 1-3 mm and macroscopically visible; arbitrarily, foci larger than that are usually not termed focal necrosis.

fo·cal ne·cro·sis

(fō'kăl nĕ-krō'sis)
Occurrence of numerous small, well-circumscribed zones of tissue that manifest coagulative, caseous, or gummatous necrosis.

focal necrosis

Necrosis in small scattered areas, often seen in infection.
See also: necrosis
References in periodicals archive ?
The histological findings of acute hepatitis and focal necrosis and zonal necrosis were reversed 10% to 20% in groups A2 and B2 at 30th days.
In the single events we found out focal necrosis (Figures 1(e)-1(f)).
In Zones 1 and 2, the most significant alterations in the two species comprised an increase in the number of melanomacrophagous centers (MMCs), fatty degeneration, inflammation, hepatitis, congestion of the blood vessels and focal necrosis. Similar results have been obtained for contaminated natural environments with adequate water quality in studies involving Pleuronectos vetulus (STEHR et al., 2003), some cyprinids species (GUL et al., 2004) and Salmo trutta f.
Core biopsies microscopically showed a tumour with vague trabecular architecture, bands of fibroblastic stroma and focal necrosis. Neoplastic cells were large, granular and glycogen rich.
Minor or un noticed pressure due to vomiting, bending or coughing in addition to splenic congestion, infarction and focal necrosis leads to distension of the splenic capsule and rupture.
In the study of biopsies in patients with moderate HBV activity, above described changes were more pronounced with the formation of focal necrosis with marked inflammatory cell infiltration of some portal tracts.
Histopathological changes in the liver of rats Microscopic observation Control Galactorsamine Silymarine 400 25 mg / kg mg / kg Hepatocyte - + + + + [Perpendicular to] degeneration Henpatic - + + + + - cell injury Parenchyma - + + + + - inflammatory Focal necrosis - + + + + - Vascular - + + + + - swelling Microscopic observation 50% Ext.
* Focal necrosis, microvascular thrombosis, and leukocytes in the debrided tissue exam References
She had no history of asthma; and she had a history of renal AML and received right nephroureterectomy in 2002 (the tumor was composed of smooth muscle, fat, thick-walled blood vessels, and cut surfaces showed focal necrosis [Figure 1]a.
These data included donor age, gender, body mass index (BMI), biopsy findings (hydrops, sinusoidal dilatation, pigment accumulation, inflammatory infiltration, parenchymal focal necrosis, microvesicular steatosis, and macrovesicular steatosis), graft type, volumetric analysis of the liver calculated by multi-slice computerized tomography (CT) [total liver volume (TLV), functional liver volume (FLV), graft volume (GV), remnant liver volume (RLV), percentage of remnant liver volume to total liver (RLV%), remnant liver to donor body weight ratio (RLBWR)], graft weight after hepatectomy (GW), peri-operative use of blood transfusion, fresh frozen plasma (FFP), amounts of crystalloid and colloid solutions, operation time, as well as intraoperative and postoperative complications.
Magnetic resonance imaging showed a heterogeneous solidcystic tumor mass with focal necrosis, measuring 9.6 cm in the greatest dimension.
The liver sections of Labeo rohita exhibited aggregation, hypertrophy of hepatocytes, cytoplasmic degeneration, hemolysis between hepatocytes, focal necrosis and degeneration.