Patients with deranged renal functions, extra hepatic malignancy, pregnancy, known history or showed hypersensitivity to contrast agent and patients whose
focal lesions was cyst or abscess were excluded from study.
The sonographic findings showed homogenous thyroid gland with no
focal lesion or abnormal vascularity seen.
This
focal lesion has alternating concentric layers of T2 weighted hypo- and hyperintensities [4].
A control utrasound was performed 10 days later (Aplio SSA-770A; Toshiba Medical, Tokyo, Japan), still showing a
focal lesion in the left liver lobe, about 4 cm in diameter, with irregular and spiky margins, oval in shape, with a thin hyperechogenic capsule, with an inhomogeneous structure and a few smaller lesions of different echogenicity (characterized as a nodule within a nodule) (Figure 5).
Poole, "The pathobiology of
focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis," Arthritis & Rheumatism, vol.
A paternally inherited ABCC8 mutation was identified in the patient with a
focal lesion (case 4).
Look out for a
focal lesion which is up to 2mm in diameter.
In 41 of the 72 (57%) lesions vascular occlusion was noted, which was defined as an interruption of a vessel at the border of a
focal lesion (without depiction of the vessel) or peripheral to the lesion (Figure 2A,B).
Vagus nerve stimulation is used for cases where a
focal lesion or focal epilepsy cannot be established.
In focal HI, which accounts for approximately 40% to 60% of all cases of [K.sub.ATP]-HI, there is a loss of heterozygosity involving a paternally derived mutation of the ABCC8 or KCNJ11 gene and a specific loss of maternal alleles of the imprinted chromosome region 11p15 resulting in a
focal lesion (focal adenomatosis) (18).