focal glomerulonephritis

fo·cal glo·mer·u·lo·ne·phri·tis

glomerulonephritis affecting a small proportion of renal glomeruli that commonly presents with hematuria and may be associated with acute upper respiratory infection in young males, not usually due to streptococci; associated with IgA deposits in the glomerular mesangium and may also be associated with systemic disease, as in Henoch-Schönlein purpura.

Synonym(s): Berger disease, Berger focal glomerulonephritis, focal nephritis, IgA nephropathy

fo·cal glo·mer·u·lo·ne·phri·tis

(fō'kăl glō-mer'yū-lō-nĕ-frī'tis)

Glomerulonephritis affecting a small proportion of renal glomeruli that commonly presents with hematuria and may be associated with acute upper respiratory infection in young males, not usually due to streptococci; associated with IgA deposits in the glomerular mesangium and may also be associated with systemic disease, as in Henoch-Schönlein purpura.
Synonym(s): Berger disease, Berger focal glomerulonephritis.

Berger,

Jean, 20th century French nephrologist.

Berger disease - Synonym(s): focal glomerulonephritis

Berger focal glomerulonephritis - Synonym(s): focal glomerulonephritis

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References in periodicals archive ?

Thus, it appears that in majority of cases of chronic focal glomerulonephritis, there are diffuse intercapillary deposits associated with the focal lesions.

PATHOLOGY OF IgA NEPHROPATHY

He had undergone kidney transplantation more than 20 years previously following the diagnosis of focal glomerulonephritis. Renal function was stable under immunosuppressive therapy with cyclosporine A (CSA) and the patient was usually normotensive.

Brain death in a septic patient: possible relationship with posterior reversible encephalopathy syndrome?

Although on light microscopic examination, histologic features such as proliferative glomerular lesions and necrotizing or crescentic lesions may be focal (focal glomerulonephritis) with some glomeruli being normal, on IF and EM examination, usually immune complex deposition is diffuse and involves even the light microscopically normal-appearing glomeruli.

Focal glomerular immune complex deposition: possible role of periglomerular fibrosis/atubular glomeruli