fluorometholone


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fluorometholone

 [floor″o-meth´o-lōn]
a synthetic glucocorticoid used topically for treatment of allergic and inflammatory conditions of the eye.

fluorometholone

A corticosteroid drug in the form of eye drops used to treat inflammatory external eye disorders. A brand name is FML.

antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.
References in periodicals archive ?
Sample powder equivalent to 5mg of fluorometholone, flumazenil, flunitrazepam, flutamide, fluvastatin sodium hydrate, and fluprednidene acetate were each dissolved in 1.0 ml dimethylsulfoxide-[d.sub.6].
For the epithelial defect, levofloxacin 0.5% ophthalmic solution (Cravit), and 0.1% fluorometholone acetate (Flarex) 4 times a day for one week were prescribed.
m/z, amu (a) Retention Collision Analyte Q1 Q3 time, min energy, V Beclomethasone dipropionate 521 337 13.2 22 Betamethasone 393 147 5.56 37 Budesonide 431 413 11.1 22 Cortisol 363 121 3.15 37 Cortisol-[d.sub.4] 367 121 3.15 37 Cortisone 361 163 3.57 37 Dexamethasone 393 147 5.92 37 Flunisolide 435 321 8.81 22 Fluorometholone 377 279 10.7 37 Fludrocortisone 381 239 3.46 37 Fluticasone propionate 501 239 12.6 22 Megestrol acetate 385 224 12.8 37 Methylprednisolone 375 161 4.90 37 Prednisolone 361 147 3.02 37 Prednisone 359 147 3.30 37 Triamcinolone 395 225 1.94 37 Triamcinolone acetonide 435 397 8.22 22 Triamcinolone-[d.sub.1] 442 404 8.07 22 acetonide-[d.sub.6] (a) amu, atomic mass units.
The improvement in Schirmer's test and TBUT test values is concordant with the studies by Avunduk et al[22] and Bragheeth and El-Kasaby, [19] which showed that dry eye patients receiving 0.1% fluorometholone plus artificial tear substitutes experienced lower symptom severity scores compared with patients receiving artificial tear substitute alone (Figure 1).
For cases of stromal and endothelial HSK, 0.1% fluorometholone eye drops (Santen, Osaka, Japan), tobramycin dexamethasone eye drops (Alcon, Puurs, Belgium), and tobramycin dexamethasone eye ointment (Alcon, Puurs, Belgium) were employed based on disease conditions.
Tenders are invited for E/D 0.1 Percent Fluorometholone
Prednisolone acetate (Predforte[R]), dexamethasone (Maxidex[R], Dexasine[R]), fluorometholone (Flarex[R], FML[R]) and loteprednol etabonate (Lotemax[R]) are the ophthalmic corticosteroids used in Turkey.
Mild dose topical steroids (fluorometholone) were used for mild iritis for a period of 3-4 days.
[31-33] In a study by Akingbehin, [16] it was shown that fluorometholone 0.1% has a substantially lower tendency to raise intraocular pressure than dexamethasone 0.1%.
(39-41) However, olopatadine may be used as an alternative to steroid therapy in GPC with recent studies showing comparable efficacy compared to the topical steroid fluorometholone. (42)
Fluorometholone (0.1%, Santen, Japan) was administered four times a day for 4 weeks after surgery, and the dose was reduced once a week.
Tenders are invited for Eye Drop Fluorometholone 0.1 Percent