fluorescent antibody test


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Related to fluorescent antibody test: FA test, indirect fluorescent antibody test

fluorescent

 [floo͡-res´ent]
pertaining to or characterized by fluorescence.
fluorescent antibody test a test for the distribution of cells expressing a specific protein by binding antibody specific for the protein and detecting complexes by fluorescent labeling of the antibody. Called also FAB test.
fluorescent treponemal antibody absorption test the standard treponemal antigen test for syphilis: Nonspecific antibodies are removed from patient serum, which is then reacted with Treponema pallidum fixed to a glass slide. Specific antibodies adhering to the treponemes are demonstrated with fluorescein-labeled antihuman globulin. Positive tests are seen in about 85 per cent of cases of primary syphilis, 100 per cent in secondary syphilis, and 98 per cent in late syphilis. The test remains positive for life even after syphilis has been successfully treated. Called also FTA-ABS test.

fluorescent antibody test

A laboratory test for the identification of a wide range of infective and other agents for which specific antibodies, linked to fluorescein, are held. The observation of fluorescence demonstrates that the antibody has attached to the corresponding substance (ANTIGEN), which must therefore be present.

Fluorescent antibody test (FA test)

A test in which a fluorescent dye is linked to an antibody for diagnostic purposes.
Mentioned in: Rabies
References in periodicals archive ?
We are indebted to the patients and their families, the staff of the Queen Elizabeth Central Hospital, and the Central Veterinary Laboratory Lilongwe for their support; Lorraine McElhinney and Denise Marston for assisting with the RNA extractions for PCR analysis and subsequent phylogenetic analysis; Sharon Brookes and Graham Parsons for assisting with the fluorescent antibody test, rabies tissue culture inoculation test, and mouse inoculation tests on submitted brain samples; and David Chadwick and Anthony Hart for support.
The fluorescent antibody test used as a diagnostic test for rabies can only indicate the presence of lyssavirus antigens and cannot distinguish between lyssavirus genotypes.
Comprehensive viral culture was established for all specimens negative for respiratory viruses by direct fluorescent antibody test.
Among the laboratory tests recommended by the World Health Organization (WHO), the fluorescent antibody test (FAT) is the accepted standard for rabies diagnosis (1).
kuhiii 1 0 1 0 Taphozous saccolaimus 6 0 2 4 * DFAT, direct fluorescent antibody test; MIT, mouse inoculation test.
Compared to the direct fluorescent antibody test, the traditional standard in rabies diagnosis, the dRIT was 100% sensitive and specific.
The specimens tested for virus yielded 14 virus strains identified as eastern equine encephalitis (EEE) virus by indirect fluorescent antibody test using a panel of alphavirus monoclonal antibodies including EEE virus complex-specific (1B1C-4) and North American EEE virus-specific (1B5C-3) monoclonal antibodies [1].
Polymerase chain reaction and direct fluorescent antibody tests were inconclusive because of the deteriorated condition of the carcass.
Rapid methods such as polymerase chain reaction assays, direct fluorescent antibody tests, and viral cultures are now available.

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