fluorescein


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fluorescein

 [floo͡-res´ēn]
a fluorescing dye; the sodium salt is used as a contrast medium in retinal angiography and as a diagnostic aid for revealing corneal lesions and fitting contact lenses.

fluor·es·ce·in

(flōr-es'ē-in), [C.I. 45350]
An orange-red crystalline powder that yields a bright green fluorescence in solution and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow.

fluorescein

(flo͝o-rĕs′ē-ĭn, flô-, flō-)
n.
An orange-red compound, C20H12O5, that exhibits intense fluorescence in alkaline solution and is used in medicine for diagnostic purposes, in oceanography as a tracer, and as a textile dye.

fluor·es·ce·in

(flōr-es'ē-in)
[C.I. 45350] An orange-red crystalline powder that yields a bright green fluorescence in solution, and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow and to visualize corneal abrasions or ulcers.

fluorescein

A green dye that fluoresces bright yellow in blue or ultraviolet light. It is used to tag (label) and thus show up ANTIBODIES in tissues. It is also much used by eye specialists (ophthalmologists) to show up ulcers on the cornea and to delineate for photography the blood vessels of the retina. For the latter purpose, the due is injected rapidly into the bloodstream (fluorescein angiography). The drug is on the WHO official list. Brand names are fluorescein, Minims fluorescein, Minims lignocaine (lidocaine, a local anaesthetic) and fluorescein, and Minims proxymetacaine (a local anaesthetic) and fluorescein.

Fluorescein

A brand name for FLUORESCEIN.

Fluorescein

A fluorescent chemical used to examine the cornea.
Mentioned in: Corneal Ulcers

fluorescein

A fluorescent, weak dibasic acid with a molecular weight of 376 whose sodium salt is used in dilute solution as a dye in the fitting of contact lenses, in the detection of corneal abrasions, etc. It is a yellowish-red compound, which fluoresces a brilliant yellow-green under ultraviolet or blue illumination (Fig. F7). Syn. sodium fluorescein. See fluorexon; Burton lamp; Wood's light; rose bengal; staining; break-up time test; fluorescein test.
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cellsenlarge picture
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cells

fluor·es·ce·in

(flōr-es'ē-in)
Nontoxic, water-soluble indicator used diagnostically to trace water flow and visualize corneal abrasions.
References in periodicals archive ?
The study was undertaken to assess and evaluate the role of fluorescein angiography and underline its advantage over other conventional methods of ophthalmology in the evaluation of posterior segment diseases.
In the control group, 3.3%-23.3% of subjects had a significantly higher fluorescein test score (8 to 12), as opposed to the interventional therapy group where none of the patients had fluorescein test score >10 ([chi square]-test, p=0.009) (Table 2).
The oligonucleotide dig-d[T.sub.20] was designed with a digoxigenin molecule in its 5' end in order to be immobilized by the anti-digoxigenin antibody (TZ-S zone) while the oligonucleotide fluor-d[G.sub.20] was designed with a fluorescein molecule in its 5' end to interact with immobilized anti-fluorescein antibody (TZ-R zone).
Fluorescein angiogram provides information regarding the localization and extent of vascular disease.
Despite the use of multiple imaging modalities preoperatively in our patient, only operative exploration with the use of intrathecal fluorescein positively located the fistula.
Fluorescein leakage was characterized by increased size and intensity.
The investigators found statistically significant physician satisfaction with the use of mannitol as a bladder distention medium over oral phenazopyridine, and slightly better satisfaction compared with the use of intravenous sodium fluorescein or normal saline distention.
465 eyes were diagnosed as retinopathy by fluorescein fundus angiography, among which, 316 eyes gad non-proliferative diabetic retinopathy (67.96%); the main manifestations of retinopathy in fundus fluorescein angiography included microangioma in macular temple, angiotelectasis and non-perfusion, and the lesions might be located in the optic disk on the side of nose and upper and lower hemal arches.
Inclusion criteria was tear break up time <10 seconds, Schirmer test score of <10 mm and fluorescein staining of at least one area out of three pre-selected areas.
After the induction of anesthesia and before skin incision, 2-3 mg/kg bodyweight (3 mg/kg in first 28 cases and 2 mg/kg in late 10 cases) of 20% solution of sodium fluorescein (Guangzhou Baiyun Shan Ming Xing Pharmaceutical Company, China, National Drug number: H44023400) diluted to 1% was administered by bolus intravenous injection.
Absorption spectra for Coumarin 6, Fluorescein, and Rhodamine 6G in Triton X-100 without and with silver NPs were measured from 190 to 900 nm using UV/Visible absorption spectrometer Perkin-Elmer Lambda 4B.