flunitrazepam


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Related to flunitrazepam: gamma hydroxybutyrate

flu·ni·traz·e·pam

(flū'nī-trāz'ĕ-pam),
A benzodiazepine compound with sedative and hypnotic properties.

Flunitrazepam, said to be the most widely prescribed sedative and hypnotic in Europe, although it is not licensed for sale in the U.S., has been the subject of increasing concern as illegal distribution and abuse of the drug have spread from southern U.S. states to other parts of this country. Abuse is particularly prevalent among high school and college youth. Used alone, flunitrazepam induces mild euphoria and sedation. It is often taken with other agents, for example to enhance a heroin high or to ease the experience of coming down from a cocaine or crack high. Flunitrazepam and alcohol have a synergistic effect, producing disinhibition and amnesia when taken together. For this reason the drug may be surreptitiously added to alcoholic drinks to facilitate date rape. Part of the popularity of the drug arises from its low cost and the availability of legally manufactured pure tablets. Flunitrazepam is marketed by Hoffman-La Roche under the brand name Rohypnol. Street names include "circles," "Mexican Valium," "la rocha," "R2," "rib," "roaches," "roachies," "Roche," "roofenol," "roofies," "rope," "rophies," and "ruffies." Being under the influence of the drug is referred to as being "roached out." The effects of flunitrazepam begin within 30 minutes after ingestion, peak within 2 hours, and may persist for 8 hours or more. Adverse effects include drowsiness, confusion, amnesia, paradoxic excitement or aggressiveness, visual disturbances, hypotension, gastrointestinal upset, and urinary retention. Lethal overdose is uncommon. Continued use results in physical dependence. Withdrawal symptoms range from headache, muscle pain, restlessness, and confusion to loss of identity, hallucinations, delirium, convulsions, and cardiovascular collapse. Withdrawal seizures can occur a week or more after cessation of use. Phenobarbital has been used to ease medically supervised withdrawal. Tablets of Rohypnol currently produced by Hoffman-LaRoche dissolve slowly in beverages and release a bright blue color so as to render covert administration less feasible.

flunitrazepam

(flo͞o′nĭ-trăz′ə-păm)
n.
A powerful sedative drug, C16H12FN3O3, that is illegal in the United States but is used elsewhere as a hypnotic and in anesthesia. It is popularly known as a "date rape" drug because it can cause semiconsciousness and memory blackouts and has been used in committing sexual assault.
A benzodiazepine that is ± 10-fold more potent than Valium Route of administration Oral, pulverised/snorted
Effects Slurred speech, impaired judgement, difficulty walking, sedation, blackouts of up to 24 hours, amnesia, respiratory distress; may have paradoxic effects and trigger aggression. Overdose or death can occur if mixed with other drugs or alcohol.
It is popularly known as the ‘date-rape’ drug.
In Texas, to be under the Influence of Rohypnol is 'To Get Roached’.

flunitrazepam

Rohypnol Pharmacology A benzodiazepine which has acquired notoriety by its slang name, the date rape drug, see there.

flunitrazepam

A BENZODIAZEPINE drug of moderate length of action used for short periods to treat insomnia. A brand name is Rohypnol. The drug has acquired notoriety because of the frequency with which it has been added illegally to alcoholic drinks as an aid to rape.
References in periodicals archive ?
The Dubai Court of First Instance convicted the Nigerians of possessing the Flunitrazepam for trading purposes despite having entered not guilty pleas.
Sleeping pills Temazepam and Flunitrazepam are also banned, as are anti-anxiety drugs Lorazepam, Oxazepam and Clonazepam.
Ultimamente se denomina a esta tendencia "cultura de club" o simplemente "fiesta", por haber sido trasladada a los clubes del mundo (4); en ella predomina el consumo de 3,4-metilendioximetanfetamina (MDMA o "extasis") y sus derivados, el gammahidroxibutirato (GHB, "extasis liquido"), la metanfetamina (speed), la ketamina, el flunitrazepam, el dextrometorfano, el oxido nitroso, la lisergida (LSD) o los hongos tipo Psylocibe, durante sesiones maratonicas de baile al ritmo de la musica electronica, buscando con ello un estado trascendente de euforia, con amplificacion de sensaciones de euforia o de alucinacion (5).
Subsection 841(b)(1)(C) sets forth the ranges applicable to offenses involving all schedule I and II controlled substances, as well as to gamma hydroxybutyric acid and a certain quantity of flunitrazepam. Id.
Schober, "Simultaneous analysis of flunitrazepam and its major metabolites in human plasma by high performance liquid chromatography tandem mass spectrometry," Journal of Pharmaceutical and Biomedical Analysis, vol.
The electrochemical quantitative analysis of many drugs has been carried out by polarographic techniques, some of them are benzodiazepines (bromazepam, chlordiazepoxide, clonazepam, diazepam, dipotassium chlorazepate, flunitrazepam; flurazepam, lorazepam, medazepam, midazolam, nitrazepam, oxazepam, pinazepam, prazepam, temazepam, triazolam, clobazam), meprobamate, phenothiazine- thioxantene- and butyrophenone-derivatives, sulpirid, reserpine, imipramine, thioridazine, amitriptyline, imipramine, opipramol, doxepine, chlorpromazine, levopromazine, perazine, prothipendyl, chlorprothixene, triperidol, methamphetamine [5].
In August, the Public Prosecution interrogated two girl students who had in their possession 234 Flunitrazepam pills, a psychotropic substance.
The US National Institute on Drug Abuse (NIDA) in its Community Alert on Club Drugs, defined 'club drugs' as ecstasy, gamma-hydroxybutyrate (GHB), ketamine, flunitrazepam (Rohypnol), methamphetamine, and lysergic acid diethylamide (LSD).
The electrochemical quantitative analysis of many drugs has been carried out by polarographic techniques, some of them are benzodiazepines (bromazepam, chlordiazepoxide, clonazepam, diazepam, dipotas-sium chlorazepate, flunitrazepam; flurazepam, lorazepam, medazepam, midazolam, nitrazepam, oxazepam, pinazepam, prazepam, temazepam, triazolam, clobazam, meprobamate, phenothiazine thioxantene and butyrophenone-derivatives, sulpirid, reserpine, imipramine, thioridazine, amitriptyline, imipramine, opipramol, doxepine, chlorpromazine, levopr- omazine, perazine, prothipendyl, chlorprothixene, triperidol, methamphetamine [5].
In contrast, the mutation did not affect the receptor's sensitivity to GABA or the modulation by zinc, the benzodiazepine flunitrazepam, or the anesthetic etomidate (Werner et al.
The court was told that anti-narcotics officers at Dubai Police received information from a source that one of the women, a 32-year-old student, had 34 pills of the illegal painkillers oxazepam and flunitrazepam.
aged 32 and 25, were arrested in March in Naif and 34 pills of Flunitrazepam were found in their possession.