The development of clinical multicolor flow cytometer
assays is currently a major undertaking.
Individual DNA molecules as small as 125 base pairs are now measurable in a simplified flow system with improved resolution and increased dynamic range using the high-sensitivity flow cytometer
developed by Habbersett and James Jett, technical staff members at LANL.
The acronym FACS (pronounced just like FAX) stands for Fluorescence Activated Cell Sorter and is a trademark of Becton-Dickinson Corporation--a $5B manufacturer of flow cytometers
and other bio-imaging devices.
To compare the two methods, precision measurements for RBCs and WBCs were performed with low, intermediate, and high cell numbers with the UF-100 flow cytometer
and the KOVA cell chamber system (Fig.
As stained DNA fragments are run through the flow cytometer
, they trigger brief bursts of fluorescence.
San Diego, CA, June 01, 2012 --(PR.com)-- NanoSort Inc., is developing next generation flow cytometers
and cell sorters that are small, simple, and affordable.
are used throughout biomedical science to measure the physical and biochemical characteristics of cells.
A flow cytometer
is an instrument capable of measuring the fluorescence of fluorescently labeled particles and biological cells one at a time (10).
The researchers accomplished the unprecedented tally by combining two extremely sensitive technologies: a laser-driven flow cytometer
capable of separating different types of cells with about 99 percent accuracy, and the polymerase chain reaction, which can detect extremely small quantities of specific DNA sequences such as those from HIV.
ACEA Biosciences' NovoCyte flow cytometer
system addresses a full range of multi-parameter cellular analysis research needs with high performance at a low cost, making it more attainable for researchers to have benchtop flow cytometers
in their labs.
In addition, the high-end flow cytometer
market has been able to accommodate the demand for easier to use, faster and more flexible instruments, expanding product lines and generating new applications.