Continuous cerebral blood
flow autoregulation monitoring in patients undergoing liver transplantation.
The pathophysiology of PRES is thought to involve disruption to cerebral blood
flow autoregulation, endothelial dysfunction, and vasogenic edema (1).
Zweifel et al., "Real time continuous monitoring of cerebral blood
flow autoregulation using near-infrared spectroscopy in patients undergoing cardiopulmonary bypass," Stroke, vol.
pneumoniae bacteremia on cerebral blood
flow autoregulation in rats," Journal of Cerebral Blood Flow & Metabolism, vol.
During the initial stages of hemorrhagic stroke, including intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), the reflex mechanisms are activated to protect cerebral perfusion, but secondary dysfunction of cerebral
flow autoregulation will eventually reduce global CBF and the delivery of metabolic substrates, leading to generalized cerebral ischemia, hypoxia, and ultimately, neuronal cell death.
de Riva et al., "The relationship between cerebral blood
flow autoregulation and cerebrovascular pressure reactivity after traumatic brain injury," Neurosurgery, vol.
Elevated SUA can induce renal vasoconstriction and impair autoregulation, which adversely affects renal blood
flow autoregulation and the glomerular filtration rate (GFR).
Propofol total intravenous anesthesia (TIVA) maintains cerebral blood
flow autoregulation and is considered superior to inhalant agents as an anesthetic protocol for patients with intracranial lesions.
[2] This syndrome is a clinico-neuroimaging entity and is hypothesised to be related to impaired cerebral blood
flow autoregulation that leads to either over- or under-perfusion of the brain.
PRES may be associated with a failure in cerebral blood
flow autoregulation combined with endothelial dysfunction (5).
Retinal blood
flow autoregulation in response to an acute increase in blood pressure.
The cerebral blood
flow autoregulation mechanism is intact CA when PRx is negative.