Succinate dehydrogenase assembly factor 2 (SDHAF2) adds a flavin adenine dinucleotide (FAD) cofactor to SDHA to form an active SDHA flavoprotein
. [alpha]-Ketoglutarate is converted by [alpha]-ketoglutarate dehydrogenase ([alpha]-KGDH) to succinyl-CoA, which in turn is converted by succinyl-CoA synthetase (SCS) to succinate.
Furthermore, recent work has shown that the dynamics of flavoprotein
fluorescence can be optically mapped in wild-type CNS tissue as an indicator of oxidative metabolism [15,16], which might be also a useful tool in experimental stroke research.
Ct values of genes of interests were normalised against the averaged Ct values of two housekeeping genes (succinate dehydrogenase complex flavoprotein
subunit A (SDHA) and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ)).
 Human Genes: IDH1, isocitrate dehydrogenase 1; IDH2, isocitrate dehydrogenase 2; L2HGDH, L-2-hydroxyglutarate dehydrogenase; SDH, succinate dehydrogenase; ZEB1, zinc finger E-box binding homeobox 1; FH, fumarate hydratase; SDHA, succinate dehydrogenase complex flavoprotein
subunit A; SDHB, succinate dehydrogenase complex iron sulfur subunit B; SDHC, succinate dehydrogenase complex subunit C; SDHD, succinate dehydrogenase complex subunit D; SDHAF1, succinate dehydrogenase complex assembly factor 1; SDHAF2, succinate dehydrogenase complex assembly factor 2.
It is hypothesized that the antioxidant functionality of riboflavin has been complemented by way of direct free radical scavenging as well as its nature of being a part of the flavoprotein
family, such as glutathione reductase.
FMO is a flavoprotein
containing a single flavin adenine dinucleotide (FAD), as a prosthetic group.
NADH Dehydrogenase: Flavoprotein
that reversibly oxidizes NADH to [NAD.sup.+] in mitochondria, in the metabolic pathway that cells use to oxidize nutrients, thereby releasing energy to reform ATP.
The also enriched succinate dehydrogenase complex, subunit A, flavoprotein
(SDHA), a potential tumor suppressor , was not found to be differentially expressed in normal versus PCa tissue .
Espinosa-Ruiz A, Belles JM, Serrano R, Culianez-Macla V (1999) Arabidopsis thaliana AtHAL3: a flavoprotein
related to salt and osmotic tolerance and plant growth.
Ortiz de Montellano, The Antituberculosis Drug Ethionamide is Activated by a Flavoprotein
(1966) Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein
functional as a reduced triphosphopyridine nucleotide-cytochrome P450 reductase.