flagellin


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flagellin

 [flaj´ĕ-lin]
a protein (mol. wt. approximately 40,000) occurring in the flagella of bacteria, which is composed of subunits arranged in several-stranded helix formation somewhat resembling myosin in structure, and sometimes containing ε-N-methyl lysine. Its composition varies with the species; thus flagellin antibodies are species specific.

flag·el·lin

(flaj'ĕ-lin),
Any member of a class of proteins that constitue subunits of the flagella and that contain the amino acid ε-N-methyllysine.

flagellin

(flə-jĕl′ĭn)
n.
Any of a group of proteins that are the structural components of bacterial flagella.
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References in periodicals archive ?
In addition, flagellin reads of eight strains (Table 1) were sequenced by Illumina HiSeq (Fasteris SA, Plan-les-Ouates, Switzerland), according to the protocol described by RYCHENER et al.
These systems are coordinately regulated, as QS-I inhibited QS-II and flagellin expression positively regulated LuxS.
LPS-primed BMDMs (a-d, f) and nonprimed BMDMs (e, g) were pretreated with APO or zVAD (20 [micro]M) and stimulated with (a) 150 [micro]g/mL silica for 3 h, (b) 10 [micro]M nigericin for 1 h, (c) 5 mM ATP for 1 h, (d-e) 2 [micro]g/mL poly (dA:dT) for 1 h, and (f-g) 1.5 [micro]g/mL flagellin for 3 h.
Besusso et al., "Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer," The Journal of Immunology, vol.
Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin. J Immunol 2008; 181: 586-592, doi: 10.4049/jimmunol.
H antigens are the flagellin protein subunit that polymerizes to form bacterial flagella.
However, available experimental data support the role of IAP in catalyzing the breakdown of monophosphates and detoxifying bacterial LPS, CpG DNA, and flagellin as well as extracellular nucleotides, such as UDP, resulting in lower TLRs activation and regulating inflammation and gut microbiota.
Koets et al., "Carvacrol induces heat shock protein 60 and inhibits synthesis of flagellin in Escherichia coli O157:H7," Applied and Environmental Microbiology, vol.
Lyme ELISA (NovaTec Immunodiagnostica GmbH) IgM antibodies (antigens: Flagellin recombinant and purified OspC) were elevated in serum (178 UA/ml, normal values < 24 UA/ml), whereas IgG were normal.
The host laboratory has a longstanding research programme on the mucosal adjuvant activity of a Toll-like receptor 5 agonist (namely flagellin).
Rapid detection and identification of Clostridium chauvoei by PCR based on flagellin gene sequence.
Role of Two Flagellin Genes in Campylobacter Motility.