fixed-dose combination

fixed-dose combination

A combination of two or more drugs in one capsule, injection, or tablet to simplify drug regimens and improve compliance.
References in periodicals archive ?
DOR is a non-nucleoside reverse transcriptase inhibitor, or NNRTI, under investigation as a single tablet for use in combination with other antiretroviral, or ARV, agents and as a fixed-dose combination with lamivudine, or 3TC, and tenofovir disoproxil fumarate for the treatment of HIV-1 infection in adult patients with no prior ARV treatment history.
According to the company, Trelegy Ellipta is the first once-daily single inhaler triple therapy approved for the long-term, once-daily, maintenance treatment of patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema, who are on a fixed-dose combination of fluticasone furoate and vilanterol for airflow obstruction and reducing exacerbations in whom additional treatment of airflow obstruction is desired or for patients who are already receiving umeclidinium and a fixed-dose combination of fluticasone furoate and vilanterol.
M2 EQUITYBITES-August 8, 2017-Mylan wins tentative approval for first fixed-dose combination "TLD" under PEPFAR for HIV/AIDS
At 12 weeks, 42.5% of patients in the fixed-dose combination therapy group were dear or almost clear, the primary study end point required by the FDA.
But by far the most dramatic change in prescribing has been the nearly threefold increase in the percentage of patients on fixed-dose combination therapy, he noted.
to develop a fixed-dose combination of three HIV medicines.
This fixed-dose combination provides a dual mechanism of action in a single tablet that can address both underlying causes of hyperuricemia - overproduction and underexcretion of serum uric acid.
M2 EQUITYBITES-July 27, 2017-Mylan introduces MyHep All in India in fixed-dose combination for treating HCV infection
This relationship was significant when the patients were using a fixed-dose combination in a single pill and also when they were using a free combination regimen with two concurrent pills, according to a poster presentation by Fadia T.
According to the company, TLE400 is an antiretroviral (ARV) fixed-dose combination and will be available in developing countries as a first-line regimen for people being treated for HIV/AIDS.