fixed drug eruption


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Related to fixed drug eruption: erythema multiforme

fixed drug e·rup·tion

a type of drug eruption that recurs at the same site (or sites) following the administration of a particular drug; the lesions usually consist of intensely erythematous and purplish, sharply demarcated macules, and occasionally of herpetic vesicles; the affected areas undergo gradual involution, but flare and enlarge on readministration of the offending drug and may become hyperpigmented.

fixed drug eruption

well-defined red to purple lesions that appear at the same sites on the skin and mucous membranes each time a particular drug is used. The reaction occurs most commonly in patients who are using tetracycline or phenolphthalein.
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Fixed drug eruption

fix·ed drug e·rup·tion

(fikst drŭg ĕr-ŭp'shŭn)
A type of drug eruption that recurs at a fixed site (or sites) after administration of a particular drug.

fixed drug eruption

A localized red rash with a sharp border, which follows exposure to a drug. The rash usually burns, occurs on the face or the genitals, and, if the offending agent is given again, recurs in the same location.
See also: eruption
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References in periodicals archive ?
In vivo dynamics of intraepidermal CD8+T cells and CD4+T cells during the evolution of fixed drug eruption.
A rare case of fixed drug Eruption due to ondansetron
Fixed drug eruptions (FDE) are a distinct type of drug eruptions that appear as pruritic, well circumscribed, round or oval-shaped, erythematous macules or edematous plaques, and characteristically recur at the same sites upon re-exposure to the offending drug.
A case of self-treatment induced recurrent fixed drug eruptions associated with the use of different fixed dose combinations of fluoroquinolone-nitroimidazole
Table 1: Distribution of cases in relation to age and gender Age in Years Males Females Total <9 4 3 7 10-19 7 5 12 20-29 8 9 17 30-39 11 12 23 40-49 10 8 18 50 & Above 5 4 9 Total 45 41 86 Table 2: Drugs causing fixed drug eruptions Drugs No.
Clinical pattern of fixed drug eruptions in a tertiary care hospital of southern Assam: a prospective study
The most common pattern of cutaneous ADR observed was fixed drug eruption (54.
A study of various drugs causing fixed drug eruptions
Drug eruptions, Stevens-Johnson syndrome, erythema multiforme, fixed drug eruption
Cutaneous morphological patterns of adverse drug reactions: a study of 50 cases
Fixed drug eruption (FDE); Changing Scenario of incriminating drugs.
Azithromycin induced fixed drug eruption
16) Intraepidermal CD8+ T cells with an effector-memory phenotype resident in fixed drug eruption lesions have a major part to play in the development of localized tissue damage.
Fixed drug eruption-bane of a boon
Fixed drug eruptions can appear anywhere on the body as single or multiple sharply demarcated, pruritic erythematous macules (Photo 3).
Drug eruptions: is your patient's rash dangerous or benign? Photo-illustrated guide helps you identify easily treated reactions, spot 'red flags' of serious conditions
Most common clinical pattern observed was fixed drug eruptions seen in 30 cases, similarly fixed drug eruptions as most common clinical pattern was seen in other studies, Thappa et al.
Study of pattern of antibiotic induced adverse cutaneous drug reactions in a tertiary care hospital
Fixed drug eruptions are blistering or erosive allergic reactions that may appear on hair-bearing skin, mucus membranes, or modified mucus membranes.
Diagnosis of genital erosions can prove elusive. (Look to other Body Parts)
For example, fixed drug eruptions can sometimes manifest with herpeslike genital lesions, as can allergic contact dermatitis following exposure to condoms, semen, or benzocaine sprays used by some men to delay ejaculation.
Serologic test a must for suspected genital herpes: three are FDA approved. (Clinical Rounds)
Results Out of total twenty patients 9 (45%) had fixed drug eruptions 4 (20%) urticaria 3 (15%) Stevens-Johnson syndrome 2 (10%) morbilliform rashes and 2 (10%) had erythema multiforme.
Clinical profile of cutaneous drug reactions

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