first-line treatment


Also found in: Wikipedia.

first-line treatment

The initial, preferred, or best treatment for a disease. It is often the therapy that combines the best efficacy with the best safety profile and/or the lowest cost.
Synonym: first-line therapy
References in periodicals archive ?
The trial demonstrated equivalence in overall response rate for the first-line treatment of patients with CD20-positive, low tumor burden, follicular lymphoma.
US-based Incyte has treated its first patient in a phase three trial named Gravitas-301 for the first-line treatment of patients with acute graft-versus-host disease (GVHD), it was reported on Friday.
Food and Drug Administration (FDA) has accepted for Priority Review the supplemental Biologics License Application (sBLA) for KEYTRUDA (pembrolizumab), the companys anti-PD-1 therapy, for the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC) whose tumors express PD-L1, with a PDUFA, or target action, date of Dec.
Salicylic acid preparations are inexpensive and available without a prescription and are considered the first-line treatment for warts.
It added that anti-depressants remain the first-line treatment for mild and moderate depression despite a substantial weight of evidence, and advice from the Chief Medical Officer, that exercise on prescription can be as effective.
Boehringer Ingelheim has initiated a Phase III clinical study of BIBW 2992 as a first-line treatment for NSCLC (non-small cell lung cancer) patients with EGFR (epidermal growth factor receptor) mutations.
GEMZAR is indicated in combination with cisplatin (another type of chemotherapy) for the first-line treatment of patients with locally advanced (Stage IIIA or Stage IIIB) or metastatic (Stage IV or cancer that has spread) non-small cell lung cancer for whom surgery is not possible.
The new indication is for first-line treatment of B-cell chronic lymphocytic leukemia (B-CLL), the leading form of adult leukemia.
This is exactly what has happened recently, when evidence became available about its use as a first-line treatment.
There isn't enough evidence of safety and efficacy in many laboratories to label ablation as first-line treatment, he added.
In the survey, psychiatrists were asked to rate the appropriateness of treatments, with 9 being the treatment of choice, 7-8 being a first-line treatment, 4-6 a second-line treatment, 2-3 being a treatment rarely used, and 1 being a treatment that is never used.
Without the activism noted below, the price could have been more than twice as high--preventing the drug from ever being widely used for first-line treatment, where the need is not immediate and desperate, since other good treatments are available for these patients.