performed glaucoma
filtration surgery in rabbits [11].
The reason for a long survival rate of functional blebs in PG eyes after
filtration surgery is still unknown.
Van de Veire et al., "Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma
filtration surgery," Investigative Opthalmology and Visual Science, vol.
While descriptions of surgical management in this text are centred on more common types of glaucoma, such as paediatric, angle closure and laser approaches to management, not to mention how to deal with concurrent cataract extraction in glaucoma
filtration surgery, the text does not shy away from discussing more modern techniques such as the minute stent procedure, which aims to increase aqueous outflow at Schlemm's canal in order to reduce intraocular pressure, to cyclodestructive approaches which are reserved for patients who are unresponsive to even surgical methods of glaucoma management.
Demirok, "Changes in choroidal thickness, axial length, and ocular perfusion pressure accompanying successful glaucoma
filtration surgery," Eye, vol.
Stalmans, "The combination of PlGF inhibition and MMC as a novel anti-scarring strategy for glaucoma
filtration surgery," Investigative Ophthalmology & Visual Science, vol.
INDICATIONS: Glaucoma drainage device implantation is usually reserved for cases with refractory glaucoma, or those unlikely to respond successfully to a conventional
filtration surgery. The Indications for GDD implantation include the following:
Khaw, "New developments in the pharmacological modulation of wound healing after glaucoma
filtration surgery," Current Opinion in Pharmacology, vol.
(2) It also has a fibrotic nature which may result in failure of many interventions such as penetrating keratoplasty and
filtration surgery. However, there are few reported cases with no identified mutation of PAX6.
Wormald, "Non-penetrating
filtration surgery versus trabeculectomy for openangle glaucoma," The Cochrane Database of Systematic Reviews, vol.
Conventional glaucoma
filtration surgery have limited role in management of glaucoma after parsplana vitrectomy & silicone oil injection, so adjuvants like Mitomycin-C & 5-Flurouracil are used to prevent fibrosis & failure of trabeculectomy (20).
Afran, "Long-term evaluation of initial
filtration surgery," Ophthalmology, vol.
