in bats: current knowledge and future directions," Viruses, vol.
Viral isolation studies have characterized a divergent arenavirus associated with the disease that has envelope glycoproteins more similar to those of filoviruses
than to those of other arenaviruses.
MGL Expressed on macrophages, immature DCs (human galactose, GalNAc, Tn antigen, filoviruses
, macrophage and gonorrhea.
DeRisi is excited about another possibility: Perhaps the snake viruses are an ancient ancestor to the arenaviruses and filoviruses
. "Maybe what you're looking at is a dinosaur virus eons old," he says.
The study has for the first time shown that mammals have harboured filoviruses
for at least tens of millions of years, in contrast to the existing estimate of a few thousand.
Category A biological agents include: Variola major (smallpox), Bacillus anthracis (anthrax), Yersinia pestis (plague), Clostridium botulinum (botulism), Francisella tularensis (tularemia) and filoviruses
and arena viruses (such as Ebola and Lassa virus which result in viral hemorrhagic fever) (CDC 200511).
They also focus on the activation and evasion of host antiviral signaling pathways by detailing RNA virus families, filoviruses
, suppression of innate immunity, paramyxovirus and orthomyxoviruses, arenaviruses, picornaviruses, togaviruses, coronaviruses and innate immune responses elicited by reovirus and rotavirus.
Mishra, Director, NIV, Pune, participated in the IV International Symposium on Filoviruses
: Cellular System and Ecosystem Study towards Outbreak Assessment at Libreville (March 26-28, 2008).
were named as a result of their thread-like structure (filum is Latin for thread) and are characterized by elongated, branched, curved, or spherical virions.
Arena viruses or filoviruses
cause the viral hemorrhagic fevers including Lassa, Ebola and Marburg.
Peters CJ, Sanchez A, Feldman H, Rollin PE, Nichol ST, Ksiazek TG (1994) Filoviruses
as emerging pathogens.
The CDC also has identified an "A" list of biological agents of highest concern, which includes (a) variola major (smallpox), (b) Bacillus anthracis (anthrax), (c) Yersinia pestis (plague), (d) Francisella tularensis (tularemia), (e) botulinum toxin (botulism), and (f) filoviruses
and arenaviruses (viral hemorrhagic fevers).