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A genus in the family Filoviridae that includes Marburg and Ebola viruses.
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(fē′lō-vī′rəs, fĭl′ō-)
Any of a family of filamentous single-stranded RNA viruses, including the Ebola and Marburg viruses, that cause hemorrhagic fevers in humans and other primates and spread by contact with infected body fluids.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
References in periodicals archive ?
Hayman, "Filoviruses in bats: current knowledge and future directions," Viruses, vol.
Viral isolation studies have characterized a divergent arenavirus associated with the disease that has envelope glycoproteins more similar to those of filoviruses than to those of other arenaviruses.
MGL Expressed on macrophages, immature DCs (human galactose, GalNAc, Tn antigen, filoviruses, macrophage and gonorrhea.
DeRisi is excited about another possibility: Perhaps the snake viruses are an ancient ancestor to the arenaviruses and filoviruses. "Maybe what you're looking at is a dinosaur virus eons old," he says.
The study has for the first time shown that mammals have harboured filoviruses for at least tens of millions of years, in contrast to the existing estimate of a few thousand.
Category A biological agents include: Variola major (smallpox), Bacillus anthracis (anthrax), Yersinia pestis (plague), Clostridium botulinum (botulism), Francisella tularensis (tularemia) and filoviruses and arena viruses (such as Ebola and Lassa virus which result in viral hemorrhagic fever) (CDC 200511).
They also focus on the activation and evasion of host antiviral signaling pathways by detailing RNA virus families, filoviruses, suppression of innate immunity, paramyxovirus and orthomyxoviruses, arenaviruses, picornaviruses, togaviruses, coronaviruses and innate immune responses elicited by reovirus and rotavirus.
Mishra, Director, NIV, Pune, participated in the IV International Symposium on Filoviruses: Cellular System and Ecosystem Study towards Outbreak Assessment at Libreville (March 26-28, 2008).
Filoviruses were named as a result of their thread-like structure (filum is Latin for thread) and are characterized by elongated, branched, curved, or spherical virions.
The CDC also has identified an "A" list of biological agents of highest concern, which includes (a) variola major (smallpox), (b) Bacillus anthracis (anthrax), (c) Yersinia pestis (plague), (d) Francisella tularensis (tularemia), (e) botulinum toxin (botulism), and (f) filoviruses and arenaviruses (viral hemorrhagic fevers).