All samples were also screened for antibodies against Marburg virus (MARV) glycoprotein (MARV-GP); only 1 sample showed cross-reactivity against both filovirus
Pohlmann, "The glycoproteins of all filovirus
species use the same host factors for entry into bat and human cells but entry efficiency is species dependent," PLoS One, vol.
Challenges progress, and opportunities: proceedings of the filovirus
medical countermeasures workshop.
Recommendations for infection control while providing care to patients with suspected or confirmed Ebola haemorrhagic fever are provided in: Interim infection control recommendations for care of patients with suspected or confirmed Filovirus
(Ebola, Marburg) haemorrhagic fever, March 2008.
The first documented outbreaks of hemorrhagic fever caused by a filovirus
occurred more than 45 years ago, but the amount of virus genetic diversity in the strains indicate that the Filoviridae are much older.
The emergence of the Ebola virus, a hemorrhagic disease caused by a filovirus
, was first reported in the United States in Dallas, TX, in Thomas Eric Duncan, the first person to die of Ebola in this country.
EVD is what experts called a filovirus
disease; emerging pathogens that cause viral hemorrhagic fevers.
The Ebola virus, a filovirus
, has been shown to cause liquefaction of the adrenals .
LSECtin is coexpressed with DC-SIGNR and CD23 and binds to ebola virus, filovirus
glycoproteins, lymphocytic choriomeningitis virus, and, to the S-protein of SARS coronavirus but does not interact with HIV-1 and hepatitis C ; although a study suggested that LSECtin binds to hepatitis C virus, the interaction was in association DC-SIGNR with .