filopodia


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fi·lo·po·di·a

(fī'lō-pō'dē-ă),
Plural of filopodium.

filopodia

Bundles of actin filaments that project from the cell surface.
References in periodicals archive ?
In fact, it has been reported that (i) MMP-2 expression regulates MSC proliferation [64-66]; (ii) the actin cytoskeleton structure determines cell shape and the cytoskeleton-dependent cell morphology affects cell proliferation, in particular, actin-rich plasma membrane-associated structures, such as filopodia and small punctate structures (microspikes), are suggestive of cell spreading and that cells unable to spread show a reduced proliferation [57-60]; and (iii) cortactin, beside its role as a molecular scaffold for the formation of dynamic cortical actin-associated structures, has been shown to modulate specific molecular signalling targets involved in cell proliferation (e.g., ERK1/2) [56, 80].
Friedlander, "Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion," Investigative Ophthalmology and Visual Science, vol.
The team was able to obstruct the movement of these filopodia using gold nanoparticles specifically designed so that they only block the function of cancer cells and do not interfere with healthy cells.
(43,44) The distinction between filopodia in immature dendrites and the dendritic protrusions induced by local neurotransmitter application has not been clarified.
Ectopic expression of SLAT2 or SLAT in Jurkat T cells resulted in the expression of distinct forms of filopodia, namely, short versus long ones, respectively.
KEGG Glutathione Genes involved in <0.001 Hsa00480 metabolism glutathione metabolism Biocarta Rac-1 pathway Rac-1 is a Rho <0.001 family G protein that stimulates formation of actin- dependent structures Biocarta Rho pathway Rac-1 is a Rho 0.001 family G protein that stimulates formation of actin- dependent structures such as filopodia and lamellipodia Biocarta TNFR1 pathway Tumor necrosis 0.005 factor alpha binds to its receptor TNFR1 and induces caspase-dependent apoptosis Resources FDR Significant genes/ selected genes/all genes KEGG 0.020 25/54/70 Hsa04370 KEGG 0.022 12/26/39 Hsa00480 Biocarta 0.045 14/20/22 Biocarta 0.062 14/25/31 Biocarta 0.085 13/23/29
Moreover, cellular protrusions including lamellipodia and filopodia were disrupted through downregulation of Racl and Cdc42 in response to A2 in MKN-28 cells.
RhoU sobreexpresada estimula la progresion del ciclo celular e induce la transformacion; de hecho, estudios in vitro en celulas epiteliales mamarias transformadas y en celulas HeLa demostraron que la sobrexpresion de RhoU conduce a un aumento en la formacion de fibras de estres e incremento de filopodia. En contraste, su inhibicion resulta en menor movilidad celular [74].
This method has been used to investigate the elementary nature of [Ca.sup.2+]-induced [Ca.sup.2+] release mechanism [44], the process of [Ca.sup.2+]-dependent exocytosis [45], the phenomenon of [Ca.sup.2+]-sensitive glutamate release [46], the ability of local calcium transients to regulate the spontaneous motility of dendritic filopodia [47] and other [Ca.sup.2+] relative processes.
The spreading cells maintained physical contact with each other through filopodia. The results indicated that the morphology of fibroblasts had no significant difference among all the substrates.
Filopodia of the osteogenic bone cells enters nanotube pores and make interlocked bone implant interface.
New research shows how the finger-like structures, called filopodia, can extend themselves, contract and bend in dynamic movements.