filopodia

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fi·lo·po·di·a

(fī'lō-pō'dē-ă),

Plural of filopodium.

filopodia

Bundles of actin filaments that project from the cell surface.

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References in periodicals archive ?

In fact, it has been reported that (i) MMP-2 expression regulates MSC proliferation [64-66]; (ii) the actin cytoskeleton structure determines cell shape and the cytoskeleton-dependent cell morphology affects cell proliferation, in particular, actin-rich plasma membrane-associated structures, such as filopodia and small punctate structures (microspikes), are suggestive of cell spreading and that cells unable to spread show a reduced proliferation [57-60]; and (iii) cortactin, beside its role as a molecular scaffold for the formation of dynamic cortical actin-associated structures, has been shown to modulate specific molecular signalling targets involved in cell proliferation (e.g., ERK1/2) [56, 80].

Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation

Friedlander, "Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion," Investigative Ophthalmology and Visual Science, vol.

The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions

The team was able to obstruct the movement of these filopodia using gold nanoparticles specifically designed so that they only block the function of cancer cells and do not interfere with healthy cells.

Future Cancer Treatment Could Stop Disease From Spreading

(43,44) The distinction between filopodia in immature dendrites and the dendritic protrusions induced by local neurotransmitter application has not been clarified.

Review fluorescence imaging of synapse dynamics in normal circuit maturation and in developmental disorders

Ectopic expression of SLAT2 or SLAT in Jurkat T cells resulted in the expression of distinct forms of filopodia, namely, short versus long ones, respectively.

Identification of a Novel Alternatively Spliced Form of Inflammatory Regulator SWAP-70-Like Adapter of T Cells

KEGG Glutathione Genes involved in <0.001 Hsa00480 metabolism glutathione metabolism Biocarta Rac-1 pathway Rac-1 is a Rho <0.001 family G protein that stimulates formation of actin- dependent structures Biocarta Rho pathway Rac-1 is a Rho 0.001 family G protein that stimulates formation of actin- dependent structures such as filopodia and lamellipodia Biocarta TNFR1 pathway Tumor necrosis 0.005 factor alpha binds to its receptor TNFR1 and induces caspase-dependent apoptosis Resources FDR Significant genes/ selected genes/all genes KEGG 0.020 25/54/70 Hsa04370 KEGG 0.022 12/26/39 Hsa00480 Biocarta 0.045 14/20/22 Biocarta 0.062 14/25/31 Biocarta 0.085 13/23/29

Pathway-Driven Approaches of Interaction between Oxidative Balance and Genetic Polymorphism on Metabolic Syndrome

Moreover, cellular protrusions including lamellipodia and filopodia were disrupted through downregulation of Racl and Cdc42 in response to A2 in MKN-28 cells.

A novel peptide derived from Haliotis discus hannai inhibits the migration of MKN-28 gastric cancer cells through downregulation of [beta]-catenin signaling

RhoU sobreexpresada estimula la progresion del ciclo celular e induce la transformacion; de hecho, estudios in vitro en celulas epiteliales mamarias transformadas y en celulas HeLa demostraron que la sobrexpresion de RhoU conduce a un aumento en la formacion de fibras de estres e incremento de filopodia. En contraste, su inhibicion resulta en menor movilidad celular [74].

Transicion epitelio-mesenquima y migracion celular en celulas de la cresta neural y celulas metastasicas de carcinomas. Revision de la literatura

This method has been used to investigate the elementary nature of [Ca.sup.2+]-induced [Ca.sup.2+] release mechanism [44], the process of [Ca.sup.2+]-dependent exocytosis [45], the phenomenon of [Ca.sup.2+]-sensitive glutamate release [46], the ability of local calcium transients to regulate the spontaneous motility of dendritic filopodia [47] and other [Ca.sup.2+] relative processes.

Regulation of Cellular Molecular Signaling by Light

The spreading cells maintained physical contact with each other through filopodia. The results indicated that the morphology of fibroblasts had no significant difference among all the substrates.

Preparation and characterization of polyhydroxybutyrate-co-hydroxyvalerate/silk fibroin nanofibrous scaffolds for skin tissue engineering

Filopodia of the osteogenic bone cells enters nanotube pores and make interlocked bone implant interface.

Improving cellular response of titanium surface through electrochemical anodization for biomedical applications: a critical review

New research shows how the finger-like structures, called filopodia, can extend themselves, contract and bend in dynamic movements.