plaque

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plaque

 [plak]
1. any patch or flat area.
2. a superficial, solid, elevated skin lesion with a diameter equal to or greater than 1.0 cm (0.5 cm according to some authorities); see also papule.
atheromatous plaque fibrous plaque.
dental plaque a dense, nonmineralized, highly organized biofilm of microbes, organic and inorganic material derived from the saliva, gingival crevicular fluid, and bacterial byproducts. It plays an important etiologic role in the development of dental caries and periodontal and gingival diseases; calcified plaque forms dental calculus.
fibrous plaque the lesion of atherosclerosis, a white to yellow area within the wall of an artery that causes the intimal surface to bulge into the lumen; it is composed of lipid, cell debris, smooth muscle cells, collagen, and, in older persons, calcium. Called also atheromatous plaque.
Hollenhorst p's atheromatous emboli containing cholesterol crystals in the retinal arterioles.
pleural p's opaque white plaques on the parietal pleura, visible radiographically in cases of asbestosis.
senile p's microscopic lesions composed of fragmented axon terminals and dendrites surrounding a core of amyloid seen in the cerebral cortex in Alzheimer's disease.

plaque

(plak),
1. A patch or small differentiated area on a body surface (for example, skin, mucosa, or arterial endothelium) or on the cut surface of an organ such as the brain; in skin, a circumscribed, elevated, superficial, and solid area exceeding 1 cm in diameter.
2. An area of clearing in a flat confluent growth of bacteria or tissue cells, such as that caused by the lytic action of bacteriophage in an agar plate culture of bacteria, by the cytopathic effect of certain animal viruses in a sheet of cultured tissue cells, or by antibody (hemolysin) produced by lymphocytes cultured in the presence of erythrocytes and to which complement has been added.
3. A sharply defined zone of demyelination characteristic of multiple sclerosis.
4.
[Fr. a plate]

plaque

(plăk)
n.
1. A scaly patch on a body part, especially the skin.
2. A biofilm of bacteria in a matrix of polysaccharides and other substances on the surface of a tooth or teeth.
3.
a. A deposit of fatty material on the inner lining of an arterial wall, characteristic of atherosclerosis.
b. The material that such a deposit is composed of.
4. A deposit consisting mainly of beta-amyloid and degenerating nerve tissue, found in the brain tissue of people with Alzheimer's disease.
5. A sharply defined zone of demyelination in the central nervous system characteristic of multiple sclerosis.
6. A clear, often round patch of lysed cells in an otherwise opaque layer of a bacteria or cell culture.

plaque

Cardiology
An early lesion of atherosclerosis which may be found in persons of any age in large vessels.
 
Dentistry
A soft sticky substance on teeth composed of bacteria and saliva; an indurated soft mass of polysaccharides and bacteria—e.g., Lactobacillus acidophilus, Streptococcus mutans.

Dermatology
A flat, solid, elevated, ≥ 1.0-cm-diameter skin nodule formed either by extension or coalescence of papules of lichen amyloidosis, lichen simplex chronicus, lichen planus, or psoriasis; a “plaque” stage occurs in certain skin tumours (e.g., the second stage of Kaposi sarcoma), and evolving mycosis fungoides.
 
Molecular biology
A clear area on a lawn of bacterial cells caused by the lysis of infected cells by a phage.
 
Neuropathology
Shadow plaques—one of multiple, irregularly shaped and sharply demarcated lesions (focal demyelinisation) in the gray and white matter in the brain of patients with multiple sclerosis.

plaque

Cardiology An early lesion of ASHD found in persons of any age in larger vessels Dentistry A soft sticky substance on teeth composed of bacteria and saliva; an indurated gob of polysaccharides and bacteria–eg, Lactobacillus acidophilus, Streptococcus mutans. See Periodontitis Dermatology A flat, solid, elevated ≥ 1. 0 cm in diameter skin nodule formed either by extension or coalescence of papules of lichen amyloidosis, lichen simplex chronicus, lichen planus, psoriasis; a 'plaque' stage occurs in certain skin tumors–eg, the 2nd stages of KS, mycosis fungoides Neurology 'Shadow plaques' Multiple, irregularly shaped, and sharply demarcated lesions–focal demyelinization in the gray and white matter in the brain of Pts with MS. Asymmetric unit membrane plaque, Atherosclerotic plaque, Complicated plaque, Fibrous plaque, Multiple sclerosis, Parietal pleural plaque, Senile plaque, Shadow plaque, Soldier's plaque

plaque

(plak)
1. A patch or small, differentiated area on a body surface (e.g., skin, mucosa, or arterial endothelium) or on the cut surface of an organ such as the brain.
2. An area of clearing in a flat, confluent growth of bacteria or tissue cells.
3. A sharply defined zone of demyelination characteristic of multiple sclerosis.
[Fr. a plate]

plaque

1. An area of ATHEROMA found in the inner lining of arteries in the disease of ATHEROSCLEROSIS.
2. A sticky mixture of food debris, saliva and bacteria that persists around the necks of uncleaned teeth and is the main cause of tooth decay.

plaque

  1. a clear area in a ‘lawn’ of bacterial growth, in which the bacteria have undergone LYSIS due to BACTERIOPHAGE infection. The number of plaque-forming units in a given volume applied to the lawn can be used to calculate viral numbers in a suspension.
  2. a layer that forms on the surface of a tooth, composed of bacteria in an organic matrix (see BIOFILM). As the layer thickens, anaerobic respiration of the bacteria produces acids which dissolve the tooth enamel.

Plaque

Patches of scar tissue that form where the layer of yelin covering the nerve fibers is destroyed by the multiple sclerosis disease process.

plaque

, placque (plak)
2. Patch or small, differentiated area on body surface (e.g., skin, mucosa, or arterial endothelium) or on cut surface of an organ.
3. An area of clearing in a flat, confluent growth of bacteria or tissue cells.
[Fr. a plate]
References in periodicals archive ?
This feature helps identify lipid plaques since they are typically within a fibrous plaque.
G/G, G/C and C/C genotypes were manifested as lipid-rich plaque, fibrous plaque and calcified or ulcerated plaque respectively (Table-V).
Follow-up information was available in 10 cases excluding the case of fibrous plaque. Eight patients died of disease 4-14 months after the diagnosis.
Another 73 of the heart attack deaths resulted from clotting due to rupture of fatty plaques or erosion of fibrous plaques inside a coronary artery.
These fibrous plaques may sometimes become calcified, where mineralization may replace the entire lipid core.
"There is a widespread consensus that the more fatty streaks you have, and the thicker they get, the more likely they are to go on to fibrous plaques," says McGill.
Fibrous plaques have been identified in the coronary arteries of several men who had previously been examined for risk factors.
Atherosclerosis is a kind of systemic disease frequently seen in great vessels, and the major pathological changes are fatty streaks and fibrous plaques in tunica intima of arteries.
Fibrous plaques form below the skin of the penis which don't stretch like normal tissue when it becomes erect.
The atherosclerotic lesion typically comprises fatty streaks that later develop into fibrous plaques. The initial fatty streaks are characterized by the presence of lipid-laden foam cells, mainly macrophage in origin.
Intravascular ultrasound (IVUS) confirmed abundant fibrous plaques with plaque rupture in the lesion site [Figure 1]b.