fibrosing alveolitis

id·i·o·path·ic pul·mo·nar·y fi·bro·sis (IPF),

[MIM*178500]
an acute to chronic inflammatory process or interstitial fibrosis of the lung of unknown etiology. seen in association with collagen-vascular diseases.

fibrosing alveolitis

Pulmonology A progressive chronic inflammatory disease of adults–45 to 65, which later develops into diffuse interstitial fibrosis and honeycomb lung Prevalence 4/10,000; accounts for ±15% of honeycomb lung disease Clinical Dry cough, dyspnea, clubbed fingers; FA progresses to respiratory failure and may produce cor pulmonale PFTs Restrictive changes Complications ↑ lung CA, often peripheral adenoCA

fibrosing alveolitis

A serious lung disorder involving extensive fine scarring of, and numerous cells within, the air sacs (alveoli) of the lungs. The condition can be caused by exposure to asbestos dust, mineral dusts, fungal spores and powdered bird droppings; rheumatic disorders such as RHEUMATOID ARTHRITIS, SJÖGREN'S SYNDROME and systemic sclerosis; some of the anticancer drugs such as bleomycin and cyclophosphamide; and the heart drug amiodarone. The condition may require lung transplantation.

Liebow,

Averill A., Austrian-U.S. pulmonary pathologist, 1911-1978.
usual interstitial pneumonia of Liebow - a progressive inflammatory condition of the lung. Synonym(s): fibrosing alveolitis; Hamman-Rich syndrome; idiopathic interstitial fibrosis
References in periodicals archive ?
American Thoracic Society/European Respiratory Society Classification of Idiopathic Interstitial Pneumonia Histologic Pattern Clinical/Radiologic/Pathologic Diagnosis Usual interstitial Idiopathic pulmonary fibrosis/cryptogenic pneumonia fibrosing alveolitis Nonspecific interstitial Nonspecific interstitial pneumonia pneumonia Organizing pneumonia Cryptogenic organizing pneumonia Diffuse alveolar damage Acute interstitial pneumonia Respiratory bronchiolitis Respiratory bronchiolitis interstitial lung disease Desquamative interstitial Desquamative interstitial pneumonia pneumonia Lymphoid interstitial Lymphoid interstitial pneumonia pneumonia
Enlarged mediastinal lymph nodes in the fibrosing alveolitis of systemic sclerosis.
Observer variation in pattern type and extent of disease in fibrosing alveolitis on thin section computed tomography and chest radiography.
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressivepulmonary fibrosis.
The prognostic significance of the histologic pattern of interstitial pneumonia in patients presenting with the clinical entity of cryptogenic fibrosing alveolitis. Am J Respir Crit Care Med.
Neutrophil activation in fibrosing alveolitis: a comparison of lone cryptogenic fibrosing alveolitis and systemic sclerosis.
Kelly, "Interstitial lung disease in patients with rheumatoid arthritis: a comparison with cryptogenic fibrosing alveolitis," Rheumatology, vol.
A survey of nocturnal hypoxaemia and health related quality of life in patients with cryptogenic fibrosing alveolitis. Thorax 2001;56:482-6.
Laurent, "Adult familial cryptogenic fibrosing alveolitis in the United Kingdom," Thorax, vol.
Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lung): correlation of histology at biopsy with prognosis.