Acral
fibromyxoma (digital
fibromyxoma) is a benign dermal fibroblastic neoplasm of acral sites.
Plexiform
fibromyxoma is a recently described gastric tumor with peculiar plexiform pattern, bland spindle cells, and a myxoid stroma invading the blood vessels [1].
Morishita, "
Fibromyxoma of the rib: report of a case," Surgery Today, vol.
Since DC usually presents as a unilocular, well-defined radiolucent lesion without prominent clinical symptoms, differential diagnosis should include the radicular cyst, odontogenic keratocyst, ameloblastoma, odontogenic
fibromyxoma and odontoma (4, 9).
In Superficial Acral
Fibromyxoma, neutrophils and Epithelial component are rare but with Prominent fibrous component mixed/alternating with moderately cellular myxoid areas and EMA variably positive.
Odontogenic
fibromyxoma. Arch Otolaryngol Head Neck Surg 1995;121(7):805, 807.
(233,234) Examples include lipoma, leiomyoma, granular cell tumor, schwannoma, gangliocytic paraganglioma, glomus tumor, inflammatory myofibroblasts tumor, plexiform
fibromyxoma (plexiform angiomyxoid myofibroblasts tumor), leiomyosarcoma, angiosarcoma, Kaposi sarcoma, and synovial sarcoma, which are immunophenotypically similar to their counterparts in other locations.
The main differential diagnoses of nasal masses with similar MRI/CT findings as schwannoma include nasal polyp, malignant peripheral nerve sheath tumors (MPNST), myxoma &
fibromyxoma, Lobular Capillary hemangioma (LCH) and sarcoma.
These entities include benign lesions such as sclerotic fibroma, (2) cellular angiofibroma, (3) giant cell angiofibroma, (4) solitary fibrous tumor, (5) medallion-like dendrocyte hamartoma (plaquelike [CD34.sup.+] dermal fibroma), (6) pleomorphic fibroma, (7) cellular digital fibroma, (8) superficial acral
fibromyxoma, (9) pleomorphic hyalinizing angiectatic tumor of soft parts, (10) and malignant lesions such as dermatofibrosarcoma protuberans (DFSP).
It is also an endothelial marker and stains solitary fibrous tumor, spindle cell lipoma, superficial acral
fibromyxoma, sclerotic fibroma, Kaposi sarcoma, neurofibroma, tricholemmoma, scleromyxedema, and nephrogenic systemic fibrosis, among others.
Superficial acral
fibromyxoma (SAFM) is a rare, slow-growing, solitary, soft tissue tumor, which was initially described by Fetsch et al (1) in 2001.
Renal cell carcinoma, fibromas and
fibromyxomas are also reported as rare occurrences in the camelids with few reports of papillomas and melanomas.