FOSL1 immunohistochemistry clarifies the distinction between desmoplastic fibroblastoma and fibroma of tendon sheath
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FNAC of calcifying aponeurotic fibroma, collagenous fibroma, and fibroma of tendon sheath
showed spindle cells lying dispersed and in packed clusters against clean background, showing predominantly a spindle cell pattern.
Differential diagnosis will be tendinous xanthoma, necrobiotic granuloma, foreign body granuloma, epidermoid cyst, knuckle pad, fibroma of tendon sheath
, lipoma and ganglion cyst .
Fibroma of tendon sheath
is a solitary, slow-growing, subcutaneous tumor with a predilection for the fingers, hands, and wrists of middle-aged adults.
Fibroma of tendon sheath is an uncommon soft tissue tumor presenting as a solitary, slow-growing, firm, painless, small nodule that shows strong attachment to the tendon or tendon sheath [1-4].
About one-third of the cases present with tenderness and mild pain due to compression of the nerves underlying fibroma of tendon sheath .
The differential diagnosis of fibroma of tendon sheath may include epidermal cyst, mucinous cyst, neuroma, leiomyoma, nodular fasciitis, synovial sarcoma, and tenosynovial giant cell tumor.
The differential diagnosis for sclerosing perineurioma mainly includes fibroma of tendon sheath
, epithelioid glomus tumor, epithelioid sarcoma (Table), and highly collagenized examples of giant cell tumor of tendon sheath.