fibrogenic

fibrogenic

adjective Referring to or causing the formation of fibrous tissue; fibroplastic.
References in periodicals archive ?
These cells, when stimulated by foreign body materials and/or particles, can activate and release a cascade of proinflammatory and prooxidant mediators which in turn stimulate other cell types, especially fibroblasts, to produce a series of fibrogenic molecules responsible for the development of fibrous tissue [19, 20].
Curcumin protectsagainst radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of inflammatory and fibrogenic cytokines.
are further divided into five categories namely; toxic dusts carcinogenic (cancer causing) dusts; fibrogenic (silicosis causing) dusts; explosive dusts and nuisance dusts.2 Particles with the size of 500
Lin et al., "15-Deoxy-[[DELTA].sup.12, 14]- prostaglandin [J.sub.2] inhibits fibrogenic response in human hepatoma cells," Toxicology Letters, vol.
Sabourin et al., "Fibrogenic signals in patients with radiation enteritis are associated with increased connective tissue growth factor expression," International Journal of Radiation Oncology Biology Physics, vol.
(5) Liver biopsy fails to satisfy the more and more pronounced need for a rapid, safe and repeatable tool to monitor the fibrogenic progression of chronic liver disease.
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice.
Thannickal said the study points to a very viable treatment strategy for idiopathic pulmonary fibrosis, and researchers saw success both in mouse models of lung fibrosis and in fibrogenic cells isolated from lungs of patients with Idiopathic Pulmonary Fibrosis.
Central and peripheral fibrogenic and neurogenic sarcoma of the oral regions.
In line with some studies, data generated in the present work revealed that following C[Cl.sub.4] administration to rats, a marked increase in the levels of oxidant, inflammatory fibrogenic mediators, TNF-[alpha], XO, and NO accompanied by an increase in MDH level (product of lipid peroxidation) in livers of C[Cl.sub.4]-treated rats (G3) compared with normal healthy ones (G1 and G2), indicating an inflammatory oxidative stress induced in liver as a target organ affected by C[Cl.sub.4] toxicity (Tanaka et al.
Its role in fibrogenesis suggests this protein as a potential fibrogenic marker, because (i) CTGF is a downstream mediator of TGF-[beta], which is the most important fibrogenic cytokine (3); (ii) CTGF is expressed increasingly in the major profibrogenic cell type, i.e., hepatic stellate cells, during their transdifferentiation in extracellular matrix-producing myofibroblasts (4, 5); (iii) expression of CTGF is strongly upregulated in fibrotic liver tissue (4, 5); and (iv) CTGF is secreted into the extracellular space and, thus, can reach the systemic circulation directly.
Fibrogenic potential of slags used as substitutes for sand in abrasive blasting operations.