fibrodysplasia

(redirected from fibrodysplasia ossificans)

fibrodysplasia

 [fi″bro-dis-pla´zhah]
abnormality in development of fibrous connective tissue.

fi·bro·dys·pla·si·a

(fī'brō-dis-plā'zē-ă),
Abnormal development of fibrous connective tissue.
References in periodicals archive ?
BioCryst has several ongoing development programs including BCX7353, an oral treatment for hereditary angioedema, BCX9930, an oral Factor D inhibitor for the treatment of complement-mediated diseases, galidesivir, a potential treatment for Marburg virus disease and Yellow Fever, and a preclinical program to develop oral ALK-2 inhibitors for the treatment of fibrodysplasia ossificans progressiva.
Ability of PGD to identify fibrodysplasia ossificans progressive (FOP) and other rare diseases could be one of the positive factors augmenting the demand in the market.
Kaplan, a renowned surgeon who was awarded Dh250,000 for his research work on fibrodysplasia ossificans progressiva (FOP) by the Grand Hamdan International Award, has donated the money as a gift in memory of his parents.
agonist, for the prevention of heterotopic ossification (HO) associated with flare up symptoms in adults and children with fibrodysplasia ossificans progressiva (FOP).
The company is preparing for a 2019 NDA submission to the FDA to seek approval of its lead product candidate, palovarotene, a novel RARI[sup.3] agonist, for the prevention of heterotopic ossification associated with flare up symptoms in adults and children with fibrodysplasia ossificans progressiva.
Heterotopic bone formation plays a major role in the extrinsic causes of stiff elbow and has been depicted to arise in several situations including traumatic (intra-articular or extra-articular fractures, dislocations, post-surgery), neurogenic (head or spinal trauma) and congenital (fibrodysplasia ossificans progressiva) conditions andsevere burns (1-5).
Palovarotene is being developed for the treatment of fibrodysplasia ossificans progressiva (FOP), multiple osteochondromas (MO) and other diseases.
Ipsen (IPSEY) and Clementia Pharmaceuticals (CMTA) announced that they have entered into an agreement for Ipsen to acquire Clementia Pharmaceuticals, including its key late-stage clinical asset palovarotene, an investigational retinoic acid receptor gamma selective agonist, for the treatment of fibrodysplasia ossificans progressiva, multiple osteochondromas and other diseases.
Case characteristics were as follows: (1) main problems of this patient were abnormal gait and limited activities; (2) the atopic bone was most likely derived from posttraumatic ossifying myositis rather than fibrodysplasia ossificans progressiva; and (3) the operation was necessary to solve this condition.
Doctors had been left baffled after years of tests, but they finally diagnosed Ellis with ultra-rare fibrodysplasia ossificans progressiva (FOP), which inevitably leads to death as there is no cure.
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by progressive heterotopic ossification (HO) in connective tissues.
In addition, genetic disorders, such as fibrodysplasia ossificans progressiva and progressive osseous heteroplasia, produce multiple HO lesions.