fibrodysplasia

(redirected from fibrodysplasia ossificans)

fibrodysplasia

 [fi″bro-dis-pla´zhah]
abnormality in development of fibrous connective tissue.

fi·bro·dys·pla·si·a

(fī'brō-dis-plā'zē-ă),
Abnormal development of fibrous connective tissue.

fibrodysplasia

/fi·bro·dys·pla·sia/ (fi″bro-dis-pla´zhah) abnormality in development of fibrous connective tissue.

fibrodysplasia

fibrous dysplasia.

fibrodysplasia ossificans
see myositis ossificans.
References in periodicals archive ?
Daiichi Sankyo Company, Limited (hereafter Daiichi Sankyo) announced today that the research that it is jointly conducting with Saitama Medical University (Main campus: Hidaka-shi, Saitama Prefecture) to create innovative therapies for fibrodysplasia ossificans progressiva (FOP) has been adopted for support under the Cyclic Innovation for
Japanese researchers from Kyoto University will start the world's first clinical trial of a drug developed from iPS (induced pluripotent stem) cells with the aim of treating the rare bone disease fibrodysplasia ossificans progressiva (FOP).
Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1.
The scientists started with a very different goal: to create a cellular model to study fibrodysplasia ossificans progressiva (FOP).
Clementia Pharmaceuticals, a company focused on developing palovarotene for fibrodysplasia ossificans progressive (FOP) and other diseases, has announced top-line results from its Phase two clinical trial investigating palovarotene intended for the treatment of FOP, it was reported yesterday.
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva.
Fibrodysplasia ossificans progressive is another disease which presents with nontraumatic MO.
See: Connective Tissue Disorders; Fibrodysplasia Ossificans Progressiva
DISCUSSION: Fibrodysplasia ossificans progressiva (FOP) is a severely disabling genetically inherited disorder of connective tissue characterized by congenital malformations of the great toes (hallux valgus, malformed first metatarsal) and progressive heterotopic ossification (HO) that forms qualitatively normal bone in characteristic extraskeletal sites.
Jasmine has fibrodysplasia ossificans progressiva, FOP, which means that when her muscles, ligaments and tissue are damaged, they turn into bone.
Myositis ossificans progressiva or fibrodysplasia ossificans progressiva (FOP) is a rare connective tissue disease characterized by widespread, progressive, ectopic ossification of soft tissues (striated muscles, tendons, fasciae, ligaments and subcutaneous tissues).
One extreme example is the development of massive HO in fibrodysplasia ossificans progressive patients, in whom a mutation in BMP receptor, activin receptor-like kinase-2, results in automatic activation of BMP signaling.