fibrocystic disease


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Related to fibrocystic disease: Polycystic disease

fibrocystic disease

Breast disease
See Fibrocystic disease of breast.
 
Orthopaedics
See Fibrocystic disease of bone.

fibrocystic disease

Chronic cystic mastitis, fibrocystic disease Surgical pathology A common benign disease of the ♀ breast, first seen circa age 40, which presents as diffuse rubbery induration, punctuated by dilated ducts and variably-sized cysts Major patterns Cysts plus fibrosis; sclerosing adenosis; epithelial hyperplasia, which ↑ CA risk. See Ductal intraepithelial neoplasia.
fibrocystic disease
No risk for future cancer: FCD with adenosis–sclerosing or florid, apocrine metaplasia, cysts–macro- or microscopic, ductal ectasia, fibroadenoma, fibrosis, hyperplasia
Minimal risk for future cancer: with glandular 'crowding', ie 2-4 epithelial cells in depth, mastitis, especially periductal, squamous metaplasia
1.5-2-foldrisk of future cancer: with hyperplasia–moderate or florid, solid or papillary or in a papilloma with a fibrovascular core
2-5-foldrisk of future cancer: with atypical hyperplasia–borderline lesion, either ductal or lobular
8-10-fold ≠ risk of future invasive cancer Carcinoma-in-situ
References in periodicals archive ?
Response of fibrocystic disease to caffeine withdrawal and correlation with cyclic nucleotides with breast disease.
However, it is not known whether leptin participates in the oncogenic transformation of fibrocystic disease. As in the general population, it has been shown that circulating leptin levels in cystic fibrosis are associated with percentage of body fat [21].
This 38-page report, now available online, shows that iodine exerts a highly statistically significant beneficial effect on fibrocystic disease (P < .001).
In one study, 38 percent of mammograms were misinterpreted as normal or showing fibrocystic disease. This researcher believes there is a lack of awareness among physicians of how often mammography is falsely negative in the presence of a palpable mass.(9)
Yet, after examining a woman's breasts or reading a mammogram, a doctor may well announce that the patient has "fibrocystic disease" or "benign breast disease." This is a nonspecific diagnosis and a true misnomer.
The women herself had fibrocystic disease of the breast which is associated with an additional increased risk for breast cancer.
In several studies a relationship between fibrocystic disease (formation of breast nodules and cysts) and drinking of these beverages was detected.
Prompted by women concerned about the diagnosis of "fibrocystic disease" and about increasing health insurance premiums, the Skokie, Ill.-based College held a consensus meeting to define the relationship between fibrocystic changes and breast cancer.
Deepa H et al in their study found breast abscess in (64.3%) cases, breast lump mimicking carcinoma breast in 14.3% and fibrocystic disease in 21.4%.
(3) Other lesions can present in a similar manner, including fibroadenoma, phylloides tumor, fibrocystic disease with squamous metaplasia and metaplastic carcinoma.
Benign phyllodes tumor was present in four cases; three cases were that of fibrocystic disease. Galactocele, gynecomastia, and intraductal pailloma shared an equal incidence of two cases each.
PASH like changes is also incidentally detected with other breast lesions such as fibrocystic disease, fibroadenomas, columnar cell lesions, lobular neoplasia and in situ and invasive ductal carcinoma.