Some nonsclerotic glomeruli were accompanied by
fibrocellular crescents (b) ((a), periodic acid methenamine silver stain, original magnification 400x; (b), periodic acid-Schiff stain, original magnification 400x).
There were 11 glomeruli with large fibrous crescent, three with large
fibrocellular crescent and six with global sclerosis.
(3,6,7) JOF are characterized by
fibrocellular stroma of spindle- or stellate-shaped cells with bony trabeculae, with or without osteoblastic rimming, and lacking cementicles or a formal capsule.
The underlying connective tissue stroma shows
fibrocellular with calcified trabeculae containing osteocytes and osteoblasts, which are frequently intermingling in immature bony trabeculae (Figure 5).
Active lesions: Endocapillary hypercellularity with or without leukocyte infiltration and with substantial luminal reduction Karyorrhexis Fibrinoid necrosis Rupture of glomerular basement membrane Crescents, cellular, or
fibrocellular Subendothelial deposits identified by light microscopy (wire loops) Intraluminal immune aggregates (hyaline thrombi) Chronic lesions: Glomerular sclerosis (segmental/global) Fibrous adhesions Fibrous crescents TABLE 3: Interobserver validation studies in lupus nephritis.
Precursor cells, probably in an attempt to regenerate death retina cells, on the contrary could mature in fibroblasts that produce
fibrocellular membranes.
Microscopic examination revealed moderately dense
fibrocellular connective tissue stroma with rich vascularity, with numerous single endothelial lined dilated and engorged vessels.
ERM, also known as macular pucker or cellophane maculopathy, is an avascular,
fibrocellular membrane which grows across the macular area.
Similarly, in our patient, more than 1 year after implantation, the DES struts showed only very limited incorporation in
fibrocellular tissue and endothelial coverage was incomplete.
On the other hand, in our experience, the CHF outpatients are shown to be affected, for the most part, by hypertensive or diabetic, or hypertensive-diabetic heart disease, or merely affected by reduction, old age-related, in cardiac performance (i.e., by structural and functional deterioration descending from variable and combined effect exercised by fibrosis, hypertrophy with
fibrocellular disarray, hibernating myocardium, apoptosis, all separately or simultaneously operating in elderly heart).
Thin paraffin sections (5 [micro]m) were cut and stained with Haematoxylin and Eosin (Luna, 1968) for routine
fibrocellular architecture, Van Gieson's stain (Luna) for collagen fibers, Gomori's reticulin method (Luna) for reticular fibers and Weigert's resorcin fuchsin and orcein (Luna) stain for elastic fibers.
Renal biopsy showed
fibrocellular crescents and little evidence of diabetic glomerulosclerosis (Fig.
