Fanburg-Smith, "Giant cell fibroblastoma
: an update and addition of 86 new cases from the Armed Forces Institute of Pathology, in honor of Dr.
is an uncommon benign soft-tissue tumor, which was first described by Evans in 1995.
In our case, the initial diagnosis was thought to be fibroblastoma
or other primary cardiac tumors, but after resection of the tumor and histopathological evaluation, the diagnosisofCATswas confirmed.
Abbie, now four years old, has been fighting a rare type of cancer called fibroblastoma
since she was born and has undergone a series of major operations in her short life.
[CD34.sup.+] Spindle Cell Neoplasms and Their Differential Diagnoses Fibrohistiocytic and fibroblastic neoplasm Dermatofibrosarcoma protuberans and giant cell fibroblastoma
Myxoinflammatory fibroblastic sarcoma Solitary fibrous tumor Giant cell angiofibroma Lipofibromatosis Fibroma Superficial angiomyxoma Superficial acral fibromyxoma Cellular digital fibroma Cellular angiofibroma Superficial [CD34.sup.+] fibroblastic tumor Neural neoplasms Neurofibroma Nerve sheath myxoma Perineurioma Lipogenic neoplasms Spindle cell lipoma/pleomorphic lipomas Neoplasms of unknown lineage Pleomorphic hyalinizing angiectatic tumor of soft parts Epithelioid sarcoma Table 2.
Abbie was taken into hospital last year to remove the rare fibroblastoma
tumour, near her spine.
(4) Additional nomenclature for this lesion includes the following: congenital granular cell lesion, gingival granular cell tumor (GCT) of the newborn, congenital epulis of the newborn, (5) congenital granular cell myoblastoma, and granular cell fibroblastoma
. (6) In this study, we review the histopathologic features and differential diagnosis of CGCE.
(26) Otherwise, the histologic differential diagnosis includes squamous cell carcinoma, hemangioma, giant cell fibroblastoma
, hemangiopericytoma, or other types of heterotopic neuroglial lesions, and even these are often easily ruled out.
(114) Many histologic variants of DFPS have been described, including giant cell fibroblastoma
(115) and those with fibrosarcomatous changes (DFSPFS), associated with a significantly more aggressive clinical course.
Interestingly, other neoplasms with fibroblastic/myofibroblastic differentiation evaluated by these authors (DFSP, LGFS, desmoplastic fibroblastoma
, and fibromatosis) did not express this antigen.
Giant cell fibroblastoma
(GCF) is a recently described, locally recurring childhood tumor of the superficial soft tissues. It is currently classified with fibrohistiocytic tumors of uncertain biologic potential, although metastatic disease has never been reported.