fibroblast growth factor receptor gene

fibroblast growth factor receptor gene (FGFR),

mutation of the gene responsible for Crouzon syndrome; located at 10q25-26; gene encoded protein is a member of the tyrosine kinase receptor superfamily with high affinity for peptides in signal transduction for mitogenesis, cellular differentiation, and embryogenesis.
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The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.

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