fibroblast

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Related to fibroblast: chondroblast, Fibrocyte, myofibroblast

fibroblast

[fi´bro-blast]

an immature fiber-producing cell of connective tissue capable of differentiating into a chondroblast, collagenoblast, or osteoblast. Called also fibrocyte. adj., adj fibroblas´tic.

fi·bro·blast

(fī'brō-blast),

A stellate or spindle-shaped cell with cytoplasmic processes present in connective tissue, capable of forming collagen fibers.

fibroblast

(fī′brə-blăst′)

A cell that gives rise to connective tissue.

fi′bro·blas′tic adj.

fi·bro·blast

(fī'brō-blast)

A stellate or spindle-shaped cell with cytoplasmic processes present in connective tissue, capable of forming collagen fibers; an inactive fibroblast is sometimes called a fibrocyte.

fibroblast

A cell that generates the protein COLLAGEN, a major component of connective tissue and the main structural material of the body. Fibroblasts are important in wound healing. They can readily be cultured artificially.

fibroblast

a connective tissue cell which may differentiate into CHONDROBLASTS, COLLAGENOBLASTS or OSTEOBLASTS.

Fibroblast

A large flat cell that secretes the proteins that form collagen and elastic fibers and the substance between the cells of connective tissue.

Mentioned in: Adhesions, Antiangiogenic Therapy

fi·bro·blast

(fī'brō-blast)

Stellate or spindle-shaped cell with cytoplasmic processes present in connective tissue, capable of forming collagen fibers.

References in periodicals archive ?

There were few scattered endoneurial fibroblasts with short cytoplasmic processes throughout the endoneurium without special arrangement.

A Possible Role of Endoneurial Fibroblast-Like Cells in the Resolution of Endoneurial Oedema Following Nerve Crush Injury/ El Posible Rol de los Fibroblastos Endoneurales en la Resolucion del Edema Endoneural Despues de una Lesion por Aplastamiento Nervioso

IL-1[alpha] is a negative regulatory factor in HS formation, which can bind to fibroblasts receptors to restrain abnormal collagen accumulation (Niessen et al., 2004; Zhang et al., 2004; Xu et al., 2008).

Regulation of Collagen Metabolism in Keratinocyte-Fibroblast Organotypic Co-culture by Pressure

Moreover, in a previous study, conversion of resting fibroblasts to pro-fibrogenic myofibroblasts in response to Ang II and endothelin resulted in cardiac fibrosis (10).

YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy

bFGF significantly promoted cell proliferation and collagen expression of fibroblasts. EGF mildly promoted fibroblast proliferation and had a slight effect on collagen expression.

Effect of Optimized Concentrations of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Proliferation of Fibroblasts and Expression of Collagen: Related to Pelvic Floor Tissue Regeneration

Citation: Ichim et al., Fibroblasts as a Practical Alternative to Mesenchymal Stem Cells.

Fibroblast Cell Therapy Versus Stem Cell Therapy

Human skin fibroblast (HSF) plays an important role during the main reconstruction process of the damaged skin area.

Role of Mitogen-Activated Protein Kinases in the Formation of Hypertrophic Scar with Model of Lipopolysaccharide Stimulated Skin Fibroblast Cells

These modifications will suppress expression of fibroblast genes while activating cardiac genes by remodeling chromatin structure to allow or restrict the access of TFs to their target genes.

Direct Cardiac Reprogramming: Progress and Promise

where [V.sub.myo] and represent the membrane potential of the atrial myocyte and fibroblast, respectively, [C.sub.myo] and [C.sub.Fb] are the membrane capacitance of the myocyte and fibroblast, respectively, [I.sub.myo] is the net membrane current of the myocyte, and [I.sub.Fb] is the net membrane current of fibroblast.

Simulation of Atrial Fibrosis Using Coupled Myocyte-Fibroblast Cellular and Human Atrial Models

Inverse Correlation between Thy1 Expression and Fibroblast Proliferation.

A Profibrotic Phenotype in Naive and in Fibrotic Lung Myofibroblasts Is Governed by Modulations in Thy-1 Expression and Activation

For the cross-over experiments, fibroblast and keratinocyte monocultures were cultured as described above.

Saliva-Derived Host Defense Peptides Histatinl and LL-37 Increase Secretion of Antimicrobial Skin and Oral Mucosa Chemokine CCL20 in an IL-1[alpha]-Independent Manner

On day 7, in group A and B, 70% animals showed predominant fibroblasts. This association was found non-significant.

EFFECT OF CURCUMIN ON EPITHELIALIZATION AND COLLAGENIZATION IN INFLAMMATION

Dermal fibroblasts from these patients show increased nuclear dysmorphology and reduced proliferation; however, the efficacy of various pharmacological agents in reversing these cellular phenotypes remains unknown.

Progeroid Syndrome Patients with ZMPSTE24 Deficiency Could Benefit When Treated with Rapamycin and Dimethylsulfoxide