fibroblast


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to fibroblast: chondroblast, Fibrocyte, myofibroblast

fibroblast

 [fi´bro-blast]
an immature fiber-producing cell of connective tissue capable of differentiating into a chondroblast, collagenoblast, or osteoblast. Called also fibrocyte. adj., adj fibroblas´tic.

fi·bro·blast

(fī'brō-blast),
A stellate or spindle-shaped cell with cytoplasmic processes present in connective tissue, capable of forming collagen fibers.

fibroblast

(fī′brə-blăst′)
n.
A cell that gives rise to connective tissue.

fi′bro·blas′tic adj.

fi·bro·blast

(fī'brō-blast)
A stellate or spindle-shaped cell with cytoplasmic processes present in connective tissue, capable of forming collagen fibers; an inactive fibroblast is sometimes called a fibrocyte.

fibroblast

A cell that generates the protein COLLAGEN, a major component of connective tissue and the main structural material of the body. Fibroblasts are important in wound healing. They can readily be cultured artificially.

fibroblast

a connective tissue cell which may differentiate into CHONDROBLASTS, COLLAGENOBLASTS or OSTEOBLASTS.

Fibroblast

A large flat cell that secretes the proteins that form collagen and elastic fibers and the substance between the cells of connective tissue.

fi·bro·blast

(fī'brō-blast)
Stellate or spindle-shaped cell with cytoplasmic processes present in connective tissue, capable of forming collagen fibers.
References in periodicals archive ?
IL-1[alpha] is a negative regulatory factor in HS formation, which can bind to fibroblasts receptors to restrain abnormal collagen accumulation (Niessen et al., 2004; Zhang et al., 2004; Xu et al., 2008).
Moreover, in a previous study, conversion of resting fibroblasts to pro-fibrogenic myofibroblasts in response to Ang II and endothelin resulted in cardiac fibrosis (10).
bFGF significantly promoted cell proliferation and collagen expression of fibroblasts. EGF mildly promoted fibroblast proliferation and had a slight effect on collagen expression.
Citation: Ichim et al., Fibroblasts as a Practical Alternative to Mesenchymal Stem Cells.
Human skin fibroblast (HSF) plays an important role during the main reconstruction process of the damaged skin area.
These modifications will suppress expression of fibroblast genes while activating cardiac genes by remodeling chromatin structure to allow or restrict the access of TFs to their target genes.
where [V.sub.myo] and represent the membrane potential of the atrial myocyte and fibroblast, respectively, [C.sub.myo] and [C.sub.Fb] are the membrane capacitance of the myocyte and fibroblast, respectively, [I.sub.myo] is the net membrane current of the myocyte, and [I.sub.Fb] is the net membrane current of fibroblast.
On day 7, in group A and B, 70% animals showed predominant fibroblasts. This association was found non-significant.
Dermal fibroblasts from these patients show increased nuclear dysmorphology and reduced proliferation; however, the efficacy of various pharmacological agents in reversing these cellular phenotypes remains unknown.