1], Recent studies suggested that prolonged fibrinolytic activity
from delayed activation of plasmin beyond the initial surgical trauma might be a potential cause for HBL.
0 ml of EBC was obtained in which the following indices were detected: Total protein content (g/L) by Lowry's method, EBC proteolytic activity by the lysis of albumin, azocasein, and azocollagen by Veremeyenko's method, the content of aldehyde and ketone derivatives of 2,4-dinitrophenylhydrazone (AKDNPH) of the main and neutral character by Dubinina's method, the content of nitrogen monoxide metabolites (NMON) by Yemchenko's method (1994) in Gozhenko's modification (2002), total, enzymatic, and non-enzymatic fibrinolytic activity
by Kukharchuk's method.
Studies have consistently shown that nattokinase possesses strong fibrinolytic activity
31 The mechanism of resolution was not reported but in separate animal studies, inhibition of bradykinin generation at injury site and increase in serum fibrinolytic activity
were observed, suggesting the probable mechanism of haematoma resolution.
similarities with plasminogen, it's fibrinolytic activity
Previous literature on acute obstructive hydrocephalus has suggested that CSF with its fibrinolytic activity
increases intraventricular pressure and causes a hyperdynamic CSF flow, as well as proximal aqueduct dilatation, which can break down the clot and resolve hydrocephalus (3).
Myrtaceae), popularly known as "guavirova," which is one of the plants used in studies, exhibits a broad spectrum of physiological effects (Lorenzi, 2008), including antiplatelet, antithrombotic, and fibrinolytic activity
in mice when administered orally, compared with ASA (Klafke et al.
Primary fibrinolysis or fibrinogenolysis involves increased fibrinolytic activity
because of the imbalance between plasmin and antiplasmins in favour of the former.
Furthermore, a genetically modified bacterium with high fibrinolytic activity
(Yang et al.
It is hypothesized that the increased TG levels might lead to increased blood viscosity and altered fibrinolytic activity
, which may lead to formation of hard exudates.
Also, the increased procoagulant and fibrinolytic activity
, suggesting increased fibrin generation and turnover, increased plasma levels of urokinase-type plasminogen activator and platelets deficient in GPI-linked proteins activated by complement have been implicated.
The above predisposing factors in summary suggest a number of mechanisms that help explain the occurrence of dry socket which include delayed healing, increased fibrinolytic activity
, microvascular thrombosis and peripheral ischemia that decreased blood supply to the extraction site.