fibrinolysis


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fibrinolysis

 [fi″brĭ-nol´ĭ-sis]
the dissolution of fibrin by enzymatic action. adj. adj fibrinolyt´ic.
Fibrinolysis. From Copstead, 1995.

fi·bri·nol·y·sis

(fī-bri-nol'i-sis), Avoid the mispronunciation fibronoly'sis.
1. Hydrolysis of fibrin.
2. The process of dissolution of fibrin in blood clots.
[fibrino- + G. lysis, dissolution]

fibrinolysis

/fi·bri·nol·y·sis/ (fi″brin-ol´ĭ-sis) dissolution of fibrin by enzymatic action.fibrinolyt´ic

fibrinolysis

(fī′brə-nŏl′ĭ-sĭs)
n. pl. fibrinoly·ses (-sēz′)
The breakdown of fibrin, usually by the enzymatic action of plasmin.

fi′bri·no·lyt′ic (-nə-lĭt′ĭk) adj.

fibrinolysis

[fī′brinol′isis]
the process of fibrin digestion by plasmin that is the normal mechanism for the removal of fibrin clots. It is stimulated by adhesion of plasmin and tissue plasminogen activator to fibrin. fibrinolytic, adj.

fi·bri·nol·y·sis

(fī'bri-nol'i-sis)
Hydrolysis of fibrin.
[fibrino- + G. lysis, dissolution]

fibrinolysis

The use of drugs to dissolve blood clots in the circulation. Enzymes such as streptokinase or urokinase, which break down FIBRIN, are used. A combination of fibrinolysis and aspirin, given soon after a coronary attack, greatly improves the chances of survival.

Fibrinolysis

The clot dissolving portion of the coagulation process.
Mentioned in: Fibrin Split Products

fi·bri·nol·y·sis

(fī'bri-nol'i-sis)
Hydrolysis of fibrin.
[fibrino- + G. lysis, dissolution]

fibrinolysis

the dissolution of fibrin by enzymatic action.

pathological fibrinolysis
see primary fibrinolysis (below).
primary fibrinolysis
occurs with an excess of activators or decreased plasma inhibitors that cause hyperplasminemia, as in severe liver disease, heat stroke and malignancy.
secondary fibrinolysis
is a response to the widespread formation of microthrombi as in disseminated intravascular coagulation.
References in periodicals archive ?
Fibrinolysis is therefore the first choice reperfusion therapy.
The average concentrations of blood markers of fibrinolysis at baseline, immediately postexposure, and 20 hr postexposure are presented in Supplemental Material, Table S4.
49) The FDA label for EACA is more general, stating the medication is approved to enhance "hemostasis when fibrinolysis contributes to bleeding.
Fibrinolysis is investigated either by the measurement of its individual components (pro- and antifibrinolytic drivers) or through global tests designed to assess the time for clot dissolution upon addition of optimal amounts of tPA.
14,6 [+ or -] 1,1 Prothrombin time (s) 25,3 [+ or -] 1,2 Thrombin time (s) 48,0 [+ or -] 1,1 Free heparin (s) 9,3 [+ or -] 0,3 Antithrombin III (s) 45,3 [+ or -] 3,5 Fibrinogen (g/liter) 1,9 [+ or -] 0,2 Total euglobulin fibrinolysis (min) 20,0 [+ or -] 0,0 Hageman-dependent fibrinolysis (min) 320,0 [+ or -] 0,0 Ethanol sample 10 (-) Protamine sulfate sample 10(-) After infiltration of layer (fraction) Indications [OFXG.
It is the only test that can provide information on the balance of thrombosis and fibrinolysis and how these elements interact (Gonzalez, Pieracci, et al.
Blood coagulation and fibrinolysis in relation to endotoxemia in liver cirrhosis and hepatocellular carcinoma.
First, TA inhibits post-CPB plasmininduced fibrinolysis by binding to the lysine binding site on plasmin and plasminogen.
Objective: To compare levels of tissue plasminogen activator and plasminogen activator inhibitor-1 levels in patients with acute myocardial infarction and unstable angina in order to understand the use of high sensitivity C-reactive protein (hsCRP), coagulation and fibrinolysis markers for cardiovascular risk assessment.
Finally, garlic contains biologically active components that are able to enhance fibrinolysis, inhibit platelet aggregation, and diminish plasma viscosity (Harenberg et al.