fibrinoid


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fibrinoid

 [fi´brĭ-noid]
1. resembling fibrin.
2. a homogeneous, eosinophilic, relatively acellular refractile substance with some of the staining properties of fibrin.

fi·brin·oid

(fī'bri-noyd),
1. Resembling fibrin.
2. A deeply or brilliantly acidophilic, homogeneous, proteinaceous material that: 1) is frequently formed in the walls of blood vessels and in connective tissue of patients with such diseases as disseminated lupus erythematosus, polyarteritis nodosa, scleroderma, dermatomyositis, and rheumatic fever; 2) is sometimes observed in healing wounds, chronic peptic ulcers, the placenta, necrotic arterioles of malignant hypertension, and other unrelated conditions.
[fibrin + G. eidos, resemblance]

fibrinoid

(fī′brə-noid′, fĭb′rə-)
adj.
Of or resembling fibrin.
n.
A homogenous acellular material similar to fibrin, found normally in the placenta and formed in connective tissue and in the walls of blood vessels in certain disease states.

fi·brin·oid

(fī'bri-noyd)
1. Resembling fibrin.
2. A deeply or brilliantly acidophilic, homogeneous, refractile, proteinaceous material that: 1) is frequently formed in the walls of blood vessels and in connective tissue of patients with such diseases as disseminated lupus erythematosus, polyarteritis nodosa, scleroderma, dermatomyositis, and rheumatic fever; and 2) is sometimes observed in healing wounds, chronic peptic ulcers, the placenta, necrotic arterioles of malignant hypertension, and other unrelated conditions.
[fibrin + G. eidos, resemblance]

fibrinoid

1. Resembling fibrin.
2. A homogeneous, refractile, non-cellular material resembling FIBRIN that is found in the walls of blood vessels and elsewhere in certain disease processes. Fibrinoid is also found as a layer between the PLACENTA and the womb.
References in periodicals archive ?
Whereas mean and standard deviation were calculated for numerical (continuous) variables which included fibrinoid necrosis, calcification, and syncytial knots, and weight and apgar score of fetus were calculated by Student ttest.
(5) Absence of significant leukocytoclasis, neutrophil/eosinophil infiltrate and fibrinoid necrosis argues against the alternative etiology such as polyarteritis nodosa and anti-neutrophil cytoplasmic antibodies vasculitis in our patient.
(4) There is also evidence that tumefactive fibroinflammatory lesions may be predisposed by radiation therapy, (1) as evidenced by the presence of pseudoepitheliomatous hyperplasia, chronic inflammation, extensive fibrin deposition, and fibrinoid necrosis of blood vessels in this case.
As there are no specific diagnostic investigations of PAN, the diagnosis is clenched by considering the whole clinical picture with abnormal angiographic finding and biopsy findings of fibrinoid necrosis with predominant polymorphonuclear infiltrate suggestive of small to medium vessel vasculitis [8].
Comparison of the other variables (atherosis, necrosis, abruptio, edema, hemorrhage, thrombus, calcifications, fibrinoid deposits, syncytial nodes, villi/field, capillaries/villus, number of hemozoins per field, immune cells in decidua, cells in apoptosis, and expression of FAS, FASL, COX-1, HIF, VEGF, and cytokines IL-2, IL-4, IL-10, IFN-g, TNF, and TGF-b in placental blood and IL-2, IL-10, and TGF-b in maternal blood) was not statistically different according to the species of infection.
(a) Masson's trichrome staining (x200) showed intraglomerular crystalline precipitation obstructing the capillaries and crushing the mesangium together with fibrinoid thrombi.
Lues maligna is characterized by occlusion of the blood vessels with resultant fibrinoid necrosis at the dermal-subcutaneous junction.
Moreover, in few cases in coronary vessel showed fibrinoid necrosis represented by circumferential bright pink area of necrosis with protein deposition (Fig.
Results: Heavy placentae with abundant villous immaturity, chorangiosis and syncytial knots in group B and fibrinoid necrosis and calcification in group C were seen.
Endothelial injury accompanies severe elevations of BP resulting in fibrinoid necrosis of the arterioles with the deposition of platelets and fibrin, and a breakdown of the normal autoregulatory function.